Evidence map›Paper›PMID 34114561›Full record

ArticleeLife2021

Major genetic discontinuity and novel toxigenic species in

Daniel R Knight, Korakrit Imwattana, Brian Kullin, Enzo Guerrero-Araya, Daniel Paredes-Sabja, Xavier Didelot, Kate E Dingle, David W Eyre, César Rodríguez, Thomas V Riley

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Genomic and phenotypic insight intoEmerging microbes & infections · 2026
    Article
  2. BeyondEmerging microbes & infections · 2026
    Article
  3. Review
  4. Antibiotics (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Phylogenomic analysis of the collagen-like BclA proteins inApplied and environmental microbiology · 2026
    Article
  10. Relationship BetweenOpen forum infectious diseases · 2026
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Phenotypic analysis of variousApplied and environmental microbiology · 2025
    Article
  16. iScience · 2025
    Article
  17. Unique growth and morphology properties of Clade 5bioRxiv : the preprint server for biology · 2025
    Article
  18. Article
  19. Microbiology spectrum · 2025
    Article
  20. EmergingmSystems · 2025
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniel R KnightMedical, Molecular and Forensic Sciences, Murdoch University, Murdoch, Australia.ORCID 0000-0002-9480-4733
Korakrit ImwattanaSchool of Biomedical Sciences, the University of Western Australia, Nedlands, Australia.ORCID 0000-0002-2538-9775
Brian KullinDepartment of Pathology, University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-5460-1977
Enzo Guerrero-ArayaMicrobiota-Host Interactions and Clostridia Research Group, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile.
Daniel Paredes-SabjaMicrobiota-Host Interactions and Clostridia Research Group, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile.
Xavier DidelotSchool of Life Sciences and Department of Statistics, University of Warwick, Coventry, United Kingdom.ORCID 0000-0003-1885-500X
Kate E DingleNuffield Department of Clinical Medicine, University of Oxford, National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom.
David W EyreBig Data Institute, Nuffield Department of Population Health, University of Oxford, National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom.ORCID 0000-0001-5095-6367
César RodríguezFacultad de Microbiología & Centro de Investigación en Enfermedades Tropicales (CIET), Universidad de Costa Rica, San José, Costa Rica.ORCID 0000-0001-5599-0652
Thomas V RileyMedical, Molecular and Forensic Sciences, Murdoch University, Murdoch, Australia.ORCID 0000-0002-1351-3740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ToxinsBayes TheoremClostridioidesClostridioides difficileClostridium InfectionsGenome, BacterialHumansPhylogenyBacterial Toxinsclostridioides difficilegeneticsgenomicsinfectious diseasemicrobial evolutionmicrobiologypathogenicityspeciationtaxonomy

Identifiers

PMID34114561
PMCPMC8241443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.