Evidence map›Paper›PMID 34114383›Full record

ArticleJournal of periodontal & implant science2021

Localized probiotic-guided pocket recolonization in the treatment of chronic periodontitis: a randomized controlled clinical trial.

Vikram Kumar, Rameshwari Singhal, Pavitra Rastogi, Nand Lal, Shivani Pandey, Abbas Ali Mahdi

Abstract read
In one paragraph

Article in Journal of periodontal & implant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vikram KumarDepartment of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, India.ORCID https://orcid.org/0000-0001-9038-8456
Rameshwari SinghalDepartment of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, India. rameshwarisinghal@kgmcindia.edu.ORCID https://orcid.org/0000-0002-5389-7689
Pavitra RastogiDepartment of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, India.ORCID https://orcid.org/0000-0001-5894-5371
Nand LalDepartment of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, India.ORCID https://orcid.org/0000-0002-5227-5255
Shivani PandeyDepartment of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, India.ORCID https://orcid.org/0000-0002-2817-4729
Abbas Ali MahdiDepartment of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, India.ORCID https://orcid.org/0000-0002-8580-9911

Funding

Central Trial Registry of India CTRI/2017/03/008231King George's Medical University 1149/R-cell16
6 · The paper itself

Abstract

purposeThis randomized clinical placebo-controlled trial was conducted to evaluate the effectiveness of

methodsForty-eight CP patients were randomly assigned to 3 treatment groups: group 1 (SRP+placebo), group 2 (SRP+single application of probiotic), and group 3 (SRP+incremental application of probiotic). Clinical parameters were evaluated at baseline and at 8, 12, and 24 weeks, whereas biochemical parameters were measured at baseline and 12 weeks.

resultsAt 24 weeks, the probing pocket depth and clinical attachment level improved in all 3 groups from baseline with no significant intergroup differences; however, a statistically significant difference was observed in localized plaque and gingival scores between groups 1 and 3 (

conclusionsWithin its limitations, the results of this study show that incremental 3-time application of

trial registrationClinical Trials Registry - India Identifier: CTRI/2017/03/008231.

Indexed as

Gingipain cysteine endopeptidasesMatrix metalloproteinasesNitric oxidePeriodontal pocketProbioticsRandomized controlled trial

Identifiers

PMID34114383
PMCPMC8200388

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.