Evidence map›Paper›PMID 34114363›Full record

ArticlePediatric obesity2021

Anthropometry-based prediction of body composition in early infancy compared to air-displacement plethysmography.

Laurentya Olga, Inge A L P van Beijsterveldt, Ieuan A Hughes, David B Dunger, Ken K Ong, Anita C S Hokken-Koelega, Emanuella De Lucia Rolfe

Open access · hybridAbstract read
In one paragraph

Article in Pediatric obesity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Laurentya OlgaDepartment of Paediatrics, University of Cambridge, Cambridge, UK.ORCID 0000-0002-3562-0598
Inge A L P van BeijsterveldtDepartment of Pediatrics, Subdivision of Endocrinology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.ORCID 0000-0002-0204-7430
Ieuan A HughesDepartment of Paediatrics, University of Cambridge, Cambridge, UK.
David B DungerDepartment of Paediatrics, University of Cambridge, Cambridge, UK.
Ken K OngDepartment of Paediatrics, University of Cambridge, Cambridge, UK.
Anita C S Hokken-KoelegaDepartment of Pediatrics, Subdivision of Endocrinology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Emanuella De Lucia RolfeMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
University of Cambridge · GBErasmus MC · NL

Funding

Biotechnology and Biological Sciences Research Council BB/P028195/1Department of Health BRC-1215-20014Department of Health IS-BRC-1215-20014Medical Research Council MC_UU_00006/2Medical Research Council MC_UU_12015/2
6 · The paper itself

Abstract

backgroundAnthropometry-based equations are commonly used to estimate infant body composition. However, existing equations were designed for newborns or adolescents. We aimed to (a) derive new prediction equations in infancy against air-displacement plethysmography (ADP-PEA Pod) as the criterion, (b) validate the newly developed equations in an independent infant cohort and (c) compare them with published equations (Slaughter-1988, Aris-2013, Catalano-1995).

methodsCambridge Baby Growth Study (CBGS), UK, had anthropometry data at 6 weeks (N = 55) and 3 months (N = 64), including skinfold thicknesses (SFT) at four sites (triceps, subscapular, quadriceps and flank) and ADP-derived total body fat mass (FM) and fat-free mass (FFM). Prediction equations for FM and FFM were developed in CBGS using linear regression models and were validated in Sophia Pluto cohort, the Netherlands, (N = 571 and N = 447 aged 3 and 6 months, respectively) using Bland-Altman analyses to assess bias and 95% limits of agreement (LOA).

resultsCBGS equations consisted of sex, age, weight, length and SFT from three sites and explained 65% of the variance in FM and 79% in FFM. In Sophia Pluto, these equations showed smaller mean bias than the three published equations in estimating FM: mean bias (LOA) 0.008 (-0.489, 0.505) kg at 3 months and 0.084 (-0.545, 0.713) kg at 6 months. Mean bias in estimating FFM was 0.099 (-0.394, 0.592) kg at 3 months and -0.021 (-0.663, 0.621) kg at 6 months.

conclusionsCBGS prediction equations for infant FM and FFM showed better validity in an independent cohort at ages 3 and 6 months than existing equations.

Indexed as

Body CompositionPlethysmographyAdolescentAnimalsAnthropometryHumansInfantInfant, NewbornNetherlandsSkinfold Thickness

Identifiers

PMID34114363
PMCPMC7614814
OpenAlexW3171418292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.