Evidence map›Paper›PMID 34114188›Full record

ArticleEuropean journal of epidemiology2021

Different approaches to quantify years of life lost from COVID-19.

Tamás Ferenci

Abstract read
In one paragraph

Article in European journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  7. How should we speak about years of life lost (YLL) values?European journal of epidemiology · 2023
    Article
  8. Observational
  9. Article
  10. Article
  11. Article
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  13. Weeks of life lost to COVID-19, the case of the United States.Immunity, inflammation and disease · 2022
    Article
  14. Burden of COVID-19 Mortality and Morbidity in Poland in 2020.International journal of environmental research and public health · 2022
    Article
  15. Article
  16. The Author Replies.European journal of epidemiology · 2022
    Article
  17. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Tamás FerenciPhysiological Controls Research Center, Obuda University, Bécsi út 96/b, 1034, Budapest, Hungary. ferenci.tamas@nik.uni-obuda.hu.ORCID http://orcid.org/0000-0001-6791-3080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The burden of an epidemic is often characterized by death counts, but this can be misleading as it fails to acknowledge the age of the deceased patients. Years of life lost is therefore widely used as a more relevant metric, however, such calculations in the context of COVID-19 are all biased upwards: patients dying from COVID-19 are typically multimorbid, having far worse life expectation than the general population. These questions are quantitatively investigated using a unique Hungarian dataset that contains individual patient level data on comorbidities for all COVID-19 deaths in the country. To account for the comorbidities of the patients, a parametric survival model using 11 important long-term conditions was used to estimate a more realistic years of life lost. As of 12 May, 2021, Hungary reported a total of 27,837 deaths from COVID-19 in patients above 50 years of age. The usual calculation indicates 10.5 years of life lost for each death, which decreases to 9.2 years per death after adjusting for 11 comorbidities. The expected number of years lost implied by the life table, reflecting the mortality of a developed country just before the pandemic is 11.1 years. The years of life lost due to COVID-19 in Hungary is therefore 12% or 1.3 years per death lower when accounting for the comorbidities and is below its expected value, but how this should be interpreted is still a matter of debate. Further research is warranted on how to optimally integrate this information into epidemiologic risk assessments during a pandemic.

Indexed as

Life ExpectancyLife TablesMultimorbidityAgedAged, 80 and overAge DistributionCOVID-19FemaleHumansHungaryMaleMiddle AgedPandemicsSARS-CoV-2Sex DistributionCOVID-19Disease burdenMortalityMultimorbidityPYLLYears of life lost

Identifiers

PMID34114188
PMCPMC8192042

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.