Evidence map›Paper›PMID 34114118›Full record

ArticleHandbook of experimental pharmacology2022

Cutaneous Barriers and Skin Immunity.

Martin Köberle, Yacine Amar, Inga Marie Hölge, Susanne Kaesler, Tilo Biedermann

Abstract read
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In one paragraph

Article in Handbook of experimental pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Martin KöberleDepartment of Dermatology and Allergy, School of Medicine, Technical University Munich, Munich, Germany.
Yacine AmarDepartment of Dermatology and Allergy, School of Medicine, Technical University Munich, Munich, Germany.
Inga Marie HölgeDepartment of Dermatology and Allergy, School of Medicine, Technical University Munich, Munich, Germany.
Susanne KaeslerDepartment of Dermatology and Allergy, School of Medicine, Technical University Munich, Munich, Germany.
Tilo BiedermannDepartment of Dermatology and Allergy, School of Medicine, Technical University Munich, Munich, Germany. tilo.biedermann@tum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin barrier provides us with several lines of protection from outside hazards. Its most outward layers, the stratum corneum and the epidermis seal our body with an acidic, dry, and rather cool surface, hostile to microbes. Yet, there are also fine-tuned interactions between the mostly commensal microbiota on top of the skin surface, with underlying epidermal cells as well as the immune system, to preserve a healthy steady state and to initiate repair processes when necessary. We take a concise look at the recent insights on the inner workings of this complex barrier.

Indexed as

MicrobiotaSkinEpidermisImmunityMicrobiomeSkin barrierStaphylococcus

Identifiers

PMID34114118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.