ArticleAbdominal radiology (New York)2021
Correlation of gastrointestinal perforation location and amount of free air and ascites on CT imaging.
Article in Abdominal radiology (New York), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 16 citations in OpenAlex.
- Linking clinical presentation and histopathological data in perforation peritonitis.Bioinformation · 2026Article
- How disruption of the duodenum dodged detection: A tale of anatomical trickery.Trauma case reports · 2025Article
- Scoring model for the diagnosis of colorectal perforation and its differentiation from gastroduodenal perforation.Surgery today · 2025Article
- Combination of radiomic and clinical characteristics to predict mortality in patients with colorectal perforation.International journal of colorectal disease · 2025Article
- Gastric perforation with foreign body granuloma formation caused by a short hair-a case report.Frontiers in pediatrics · 2025Article
- Perforated Gastric Ulcer With GI Bleeding Secondary to Cystic Artery Pseudoaneurysm.Case reports in radiology · 2025Article
- Prediction of injury localization in preoperative patients with gastrointestinal perforation: a multiomics model analysis.BMC gastroenterology · 2024Article
- Diagnostic error rates and associated factors for lower gastrointestinal perforation.Scientific reports · 2022Article
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Authors and funding
10 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze the amount of free abdominal gas and ascites on computed tomography (CT) images relative to the location of a perforation.
methodsWe retrospectively included 172 consecutive patients (93:79 = m:f) with GIT perforation, who underwent abdominal surgery (ground truth for perforation location). The volume of free air and ascites were quantified on CT images by 4 radiologists and a semiautomated software. The relation of the perforation location (upper/lower GIT) and amount of free air and ascites was analyzed by the Mann-Whitney test. Furthermore, best volume cutoff for upper and lower GIT perforation, areas under the curve (AUC), and interreader volume agreement were assessed.
resultsThere was significantly more abdominal ascites with upper GIT perforation (333 ml, range 5 to 2000 ml) than with lower GIT perforation (100 ml, range 5 to 2000 ml, p = 0.022). The highest volume of free air was found with perforations of the stomach, descending colon and sigmoid colon. Significantly less free air was found with perforations of the small bowel and ascending colon compared to the aforementioned. An ascites volume > 333 ml was associated with an upper GIT perforation demonstrating an AUC of 0.63 ± 0.04.
conclusionUsing a two-step process based on the volumes of free air and free fluid can help localizing the site of perforation to the upper, middle or lower GI tract.
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