Evidence map›Paper›PMID 34114062›Full record

ArticleThe Journal of membrane biology2021

Maturation of the Na,K-ATPase in the Endoplasmic Reticulum in Health and Disease.

Vitalii Kryvenko, Olga Vagin, Laura A Dada, Jacob I Sznajder, István Vadász

Open access · hybridAbstract read
In one paragraph

Article in The Journal of membrane biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. TAZ (bioRxiv : the preprint server for biology · 2026
    Article
  2. Hypercapnia Effects on Lung Function.Comprehensive Physiology · 2026
    Review
  3. Connecting the Dots: AMOG/βInternational journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Wfs1Cell death & disease · 2023
    Article
  10. Review
  11. Probability that there is a mammalian counterpart of cardiac clock in insects.Archives of insect biochemistry and physiology · 2022
    Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Vitalii KryvenkoDepartment of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Olga VaginDepartment of Physiology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Laura A DadaDivision of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Jacob I SznajderDivision of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
István VadászDepartment of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany. istvan.vadasz@innere.med.uni-giessen.de.ORCID 0000-0003-1370-9783
Northwestern University · USGerman Center for Lung Research · DEUniversities of Giessen and Marburg Lung Center · DEUniversity of California, Los Angeles · US

Funding

Tissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GR Scott Budinger · 2015 to 2026
$26.9M
Role of hypercapnia on the lung airwaysR01HL147070 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SZNAJDER, JACOB I · 2019 to 2022
$1.9M
Targeting linear ubiquitination to attenuate inflammation and promote repair after IAV infectionR01HL154686 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BUDINGER, GR SCOTT, SZNAJDER, JACOB I · 2020 to 2020
$687k
NHLBI NIH HHS R01 HL147070NHLBI NIH HHS R01 HL154686NIA NIH HHS P01 AG049665
6 · The paper itself

Abstract

The Na,K-ATPase establishes the electrochemical gradient of cells by driving an active exchange of Na

Indexed as

Endoplasmic ReticulumCell MembraneIonsProtein FoldingSodium-Potassium-Exchanging ATPaseIonsSodium-Potassium-Exchanging ATPaseEndoplasmic reticulumNa,K-ATPaseProtein foldingProtein maturationUnfolded protein response

Identifiers

PMID34114062
PMCPMC8192048
OpenAlexW3169335479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.