Evidence map›Paper›PMID 34113925›Full record

ArticleMachine learning and medical engineering for cardiovascular health and intravascular imaging and computer assisted stenting : first International Workshop, MLMECH 2019, and 8th Joint International Workshop, CVII-STENT 2019, held in conj...2019

Abdominal Aortic Aneurysm Segmentation Using Convolutional Neural Networks Trained with Images Generated with a Synthetic Shape Model.

Karen López-Linares, Maialen Stephens, Inmaculada García, Iván Macía, Miguel Ángel González Ballester, Raúl San José Estepar

Open access · greenAbstract read
In one paragraph

Article in Machine learning and medical engineering for cardiovascular health and intravascular imaging and computer assisted stenting : first International Workshop, MLMECH 2019, and 8th Joint International Workshop, CVII-STENT 2019, held in conj..., 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

  1. AortaExplorer: AI-driven analysis of the aorta in CT images.Medical & biological engineering & computing · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Karen López-Linares *Vicomtech Foundation, San Sebastián, Spain.
Maialen Stephens *Vicomtech Foundation, San Sebastián, Spain.
Inmaculada GarcíaVicomtech Foundation, San Sebastián, Spain.
Iván MacíaVicomtech Foundation, San Sebastián, Spain.
Miguel Ángel González BallesterBCN Medtech, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain.
Raúl San José EsteparApplied Chest Imaging Laboratory, Brigham and Women's Hospital, Harvard medical school, Boston, USA.
Vicomtech · ESBiogipuzkoa Health Research Institute · ESBrigham and Women's Hospital · USInstitució Catalana de Recerca i Estudis Avançats · ESPompeu Fabra University · ES

Funding

The clinical impact of pulmonary vascular remodeling in smokersR01HL116473 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL, WASHKO, GEORGE R · 2013 to 2021
$5.0M
Airway Inspector: a chest imaging biomarker software platform for COPDR01HL116931 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL · 2013 to 2017
$2.2M
NHLBI NIH HHS R01 HL116473NHLBI NIH HHS R01 HL116931
6 · The paper itself

Abstract

An abdominal aortic aneurysm (AAA) is a ballooning of the abdominal aorta, that if not treated tends to grow and rupture. Computed Tomography Angiography (CTA) is the main imaging modality for the management of AAAs, and segmenting them is essential for AAA rupture risk and disease progression assessment. Previous works have shown that Convolutional Neural Networks (CNNs) can accurately segment AAAs, but have the limitation of requiring large amounts of annotated data to train the networks. Thus, in this work we propose a methodology to train a CNN only with images generated with a synthetic shape model, and test its generalization and ability to segment AAAs from new original CTA scans. The synthetic images are created from realistic deformations generated by applying principal component analysis to the deformation fields obtained from the registration of few datasets. The results show that the performance of a CNN trained with synthetic data to segment AAAs from new scans is comparable to the one of a network trained with real images. This suggests that the proposed methodology may be applied to generate images and train a CNN to segment other types of aneurysms, reducing the burden of obtaining large annotated image databases.

Indexed as

Abdominal aortic aneurysmConvolutional Neural NetworkPrincipal component analysisSegmentationSynthetic images

Identifiers

PMID34113925
PMCPMC8188890
OpenAlexW2980244487

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.