Evidence map›Paper›PMID 34113919›Full record

ArticleHeart rhythm O22021

Pregnancy-induced increased heart rate is independent of thyroid hormones.

Valérie Long, Sophie Mathieu, Céline Fiset

Open access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Valérie LongResearch Center, Montreal Heart Institute, Montreal, Canada.
Sophie MathieuResearch Center, Montreal Heart Institute, Montreal, Canada.
Céline FisetResearch Center, Montreal Heart Institute, Montreal, Canada.
Université de Montréal · CAMontreal Heart Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe heart rate increases by 10-20 beats per minute (bpm) throughout pregnancy in women, reaching maximum heart rate in the third trimester. During pregnancy, important changes in thyroid hormones also occur, with increases of up to 50% in the levels of triiodothyronine (T

objectiveThus, in the present study the potential contribution of T

methodsWe compared the heart rate between nonpregnant and pregnant mice under control conditions and after altering thyroid hormone levels with T

resultsConsistent with the clinical data, we found a 58% rise in T

conclusionBased on these results, it is unlikely that T

Indexed as

Heart rateMousePregnancyPropylthiouracilTriiodothyronine

Identifiers

PMID34113919
PMCPMC8183852
OpenAlexW3133959459

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.