Evidence map›Paper›PMID 34113899›Full record

ArticleHeart rhythm O22021

Comparison of 2-year outcomes between primary and secondary prophylactic use of defibrillators in patients with coronary artery disease: A prospective propensity score-matched analysis from the Nippon Storm Study.

Yusuke Kondo, Takashi Noda, Yasunori Sato, Marehiko Ueda, Takashi Nitta, Yoshifusa Aizawa, Tohru Ohe, Takashi Kurita

Open access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 1 country.

Yusuke KondoDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Takashi NodaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Yasunori SatoDepartment of Preventive Medicine and Public Health, Keio University School of Medicine, Tokyo, Japan.
Marehiko UedaDepartment of Cardiology, Eastern Chiba Medical Center, Chiba, Japan.
Takashi NittaDepartment of Cardiovascular Surgery, Nippon Medical School, Tokyo, Japan.
Yoshifusa AizawaDepartment of Research and Development, Tachikawa Medical Center, Niigata, Japan.
Tohru OheOkayama City Hospital, Okayama, Japan.
Takashi KuritaDepartment of Internal Medicine, Faculty of Medicine, Kindai University, Osaka, Japan.
Chiba University · JPKeio University · JPKindai University · JPNational Cerebral and Cardiovascular Center · JPNippon Medical School · JPOkayama Prefecture · JPTachikawa Medical Center · JPTeikyo University Chiba Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Nippon Storm Study was a prospective observational study designed to gather clinical data on implantable cardioverter-defibrillator (ICD) therapy in Japanese patients.

objectiveThe purpose of this subanalysis was to compare the incidence of ICD therapy in patients with left ventricular dysfunction owing to coronary artery disease (CAD) for primary and secondary prophylaxis of sudden cardiac death.

methodsWe analyzed data of 493 patients with CAD and ICDs (men, 87%; age, 68 ± 10 years; left ventricular ejection fraction, 36% ± 13%; primary prophylaxis, 36%). All patients were followed up for at least 2 years. Propensity score matching was used to select patient subgroups for comparison: 133 patients with ICD for primary prophylaxis and 133 with ICD for secondary indications.

resultsThere were no significant differences between primary and secondary prophylaxis groups with respect to the incidence of appropriate ICD therapy within 2 years (0.153 vs 0.239; hazard ratio, 1.565 [95% confidence interval (CI), 0.898-2.727];

conclusionThe incidence of ICD therapy received by patients with CAD for primary and secondary prophylaxis was not significantly different based on our propensity score-matched analysis. However, secondary-prophylaxis ICD therapy seems to be associated with a significantly higher risk for electrical storm than primary-prophylaxis ICD therapy.

Indexed as

Coronary artery diseaseImplantable cardioverter-defibrillatorNippon Storm StudyPrimary prophylaxisSecondary prophylaxis

Identifiers

PMID34113899
PMCPMC8183882
OpenAlexW3120362168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.