Evidence map›Paper›PMID 34113888›Full record

ArticleHeart rhythm O22020

High-power short-duration radiofrequency ablation of typical atrial flutter.

Mehrdad Golian, F Daniel Ramirez, Wael Alqarawi, Simon P Hansom, Pablo B Nery, Calum J Redpath, Girish M Nair, George C Shaw, Darryl R Davis, David H Birnie and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06406686 (Ablation Index in Standard vs. High Power Radiofrequency Ablation for Typical Atrial Flutter), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06406686 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Ablation Index in Standard vs. High Power Radiofrequency Ablation for Typical Atrial Flutter: A Randomized Study (AITAF)

TypeinterventionalSponsorUniversity of CalgaryRan2024 to 2025Enrolled50ConditionsAtrial Flutter, Atrial Flutter Typical, Cavotricuspid Isthmus Dependent Macroreentry TachycardiaArmsAblation of the Cavo-tricuspid isthmus for typical Atrial Flutter
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Evaluation of Two High-Power Ablation Approaches in the Management of Typical Atrial Flutter: A Retrospective Study.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Article
  3. Comparison of Two High-Power Ablation Strategies for Typical Atrial Flutter: Acute and Long-Term Outcome.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Mehrdad GolianArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
F Daniel RamirezArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
Wael AlqarawiArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
Simon P HansomArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
Pablo B NeryArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
Calum J RedpathArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
Girish M NairArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
George C ShawArrhythmia Service, Cardiovascular Institute, Allegheny Health Network, Pittsburgh, Pennsylvania.
Darryl R DavisArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
David H BirnieArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
Mouhannad M SadekArrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.
University of Ottawa · CAAllegheny Health Network · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-power short-duration (HPSD) ablation has been explored for pulmonary vein isolation. Early data suggest similar efficacy with shorter procedure times and perhaps greater safety. Data are lacking on the use of this ablation strategy for other arrhythmias.

objectiveThe purpose of this study was to evaluate the safety, efficacy, and clinical outcomes of HPSD ablation in patients with typical atrial flutter compared to those undergoing ablation with conventional settings.

methodsConsecutive patients undergoing cavotricuspid isthmus (CTI) ablation using standard power settings were compared to those performed after transitioning to HPSD ablation. Demographics, procedural details, and ablation outcomes were prospectively collected. The primary endpoint was duration of radiofrequency energy delivery. Secondary endpoints were radiation duration and analgesia requirements.

resultsA total of 114 consecutive subjects undergoing CTI ablation (57 standard power, 57 HPSD) were included. HPSD ablation and electroanatomic mapping/contact force (EAM/CF) use were associated with 66% (95% confidence interval [CI] 58%-73%) and 50% (95% CI 37%-60%) shorter ablation times compared to standard power and not using EAM/CF, respectively. Patients in the HPSD group required 50 mcg less fentanyl relative to the standard ablation arm after adjusting for sex, age, and comorbidities (

conclusionHPSD is a safe and effective approach to CTI ablation. This strategy may reduce ablation time and analgesia requirements. Larger studies and longer follow-up are needed to further evaluate this strategy.

Indexed as

AblationAtrial fibrillationAtrial flutterFluoroscopyHigh-power short-duration ablation

Identifiers

PMID34113888
PMCPMC8183899
OpenAlexW3090322746

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.