Evidence map›Paper›PMID 34113857›Full record

ArticleHeart rhythm O22020

A novel screening test for inappropriate shocks due to myopotentials from the subcutaneous implantable cardioverter-defibrillator.

Yuji Ishida, Shingo Sasaki, Yuichi Toyama, Kimitaka Nishizaki, Yoshihiro Shoji, Takahiko Kinjo, Taihei Itoh, Daisuke Horiuchi, Masaomi Kimura, Michael R Gold and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yuji IshidaDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Shingo SasakiDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Yuichi ToyamaDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Kimitaka NishizakiDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Yoshihiro ShojiDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Takahiko KinjoDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Taihei ItohDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Daisuke HoriuchiDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Masaomi KimuraDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Michael R GoldDivision of Cardiology, Medical University of South Carolina, Charleston, South Carolina.
Hirofumi TomitaDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Hirosaki University · JPMedical University of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe subcutaneous implantable cardioverter-defibrillator (S-ICD) is effective in preventing sudden cardiac death. Compared with transvenous ICDs, S-ICDs have a lower rate of inappropriate shocks (IASs) for supraventricular arrhythmias, but such shocks for T-wave oversensing (TWO) and extracardiac myopotentials are more common. No screening tests to identify patients at risk for IAS due to myopotential interference (MPI) currently are available.

objectiveThe purpose of this study was to assess the efficacy of a tube exercise test (TET) developed to detect MPI post S-ICD implantation.

methodsTET includes 3 different maneuvers using an exercise tube. S-ICD electrograms were recorded to assess MPI while patients performed each of the maneuvers.

resultsTET was performed in 43 patients, and MPI was observed in 12 patients (28%). In 10 of the 12 TET-positive patients, the positive vector corresponded with a vector that did not show TWO on standard S-ICD preoperative screening. During median follow-up of 672 days (interquartile range 465-805 days), 3 patients (7%) experienced IAS due to MPI. Importantly, the vector at the time of IAS in all 3 patients passed standard preoperative screening for TWO but was positive with TET. Sensitivity and specificity of TET were 100% and 78%, respectively, and positive and negative predictive values were 25% and 100%, respectively.

conclusionPostimplant screening for MPI identified patients at increased risk for IAS. TET may be helpful for guiding optimal programming to prevent IAS.

Indexed as

Exercise testInappropriate shockMyopotential interferenceOversensingSubcutaneous implantable cardioverter-defibrillator

Identifiers

PMID34113857
PMCPMC8183885
OpenAlexW3020332097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.