Evidence map›Paper›PMID 34113855›Full record

ArticleHeart rhythm O22020

Spatial relationship between the pulmonary trunk and the left coronaries: Systematic risk assessment based on automated three-dimensional distance measurements.

Eberhard Scholz, Christa Hartlage, Felix Bernhardt, Tobias Weber, Janek Salatzki, Florian André, Patrick Lugenbiel, Johannes Riffel, Hugo Katus, Sebastian Sager

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Cardiac phase variability in pulmonary root geometry: implications for electrophysiological mapping and ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  2. Image-Derived Modeling to Assess Coronary Proximity in Patients Undergoing Transcatheter Pulmonary Valve Replacement With Self-Expanding Valves.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Eberhard ScholzDepartment of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.
Christa HartlageDepartment of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.
Felix BernhardtInformatics for Life, Heidelberg, Germany.
Tobias WeberFaculty of Mathematics, University of Magdeburg, Magdeburg, Germany.
Janek SalatzkiDepartment of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.
Florian AndréDepartment of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.
Patrick LugenbielDepartment of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.
Johannes RiffelDepartment of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.
Hugo KatusDepartment of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.
Sebastian SagerInformatics for Life, Heidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEUniversity Hospital Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation of right ventricular outflow tract ventricular arrhythmias from above the pulmonary valve is being increasingly reported.

objectiveThe purpose of this study was to systematically analyze the spatial relationship between the pulmonary trunk and the left coronaries.

methodsContrast-enhanced computed tomographic scans from 58 patients were analyzed. After segmentation of the pulmonary trunk and the proximal left coronaries, 3-dimensional geometries were generated. Minimal distance between the pulmonary trunk and the coronaries was automatically determined using a newly developed mathematical algorithm.

resultsThe minimal distance between the pulmonary trunk and the coronaries was 1.4 ± 0.11 mm. Closest relationship was detected 13.8 ± 0.87 mm above the pulmonary valve annulus. Considering a safety margin of 5 mm to render coronary damage unlikely, 84% of patients were found to be at potential risk within the bottom 10 mm of the left sinus cusp. In contrast, positions within or above the right and anterior cusps were less likely to exhibit a close relationship. We identified the anterior aspect of the left cusp as the most critical region. Positions 10-20 mm above the left cusp were found to be critical in 97% of patients. Clinical parameters such as gender, age, height, weight, and body mass index were not predictive of a close spatial relationship.

conclusionOur data provide evidence for a close spatial relationship between the pulmonary trunk and coronary arteries. These results should be considered when performing catheter ablation from above the pulmonary valve.

Indexed as

Catheter ablationCoronary arteriesCoronary damagePulmonary sinus cuspsPulmonary trunkRight ventricular outflow tractRisk assessmentSpatial relationshipVentricular arrhythmias

Identifiers

PMID34113855
PMCPMC8183892
OpenAlexW3018642825

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.