ArticleClinical parkinsonism & related disorders2020
Goal-directed behavior in individuals with mild Parkinson's disease: Role of self-efficacy and self-regulation.
Article in Clinical parkinsonism & related disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Empowering Patients: The Role of Group Health Coaching in Improving Self-Efficacy and Well-Being in Parkinson's Disease.American journal of lifestyle medicine · 2026Article
- The feasibility of a self-regulation and mental imagery programme to enhance everyday functioning for people with Parkinson's disease: study protocol.Pilot and feasibility studies · 2024Article
- Big-five personality traits and depression: chain mediation of self-efficacy and walking.Frontiers in psychiatry · 2024Article
- Patient motivation: A concept analysis.Belitung nursing journal · 2024Article
- Training-induced circuit-specific excitatory synaptogenesis in mice is required for effort control.Nature communications · 2023Article
- Self-medication in Chinese residents and the related factors of whether or not they would take suggestions from medical staff as an important consideration during self-medication.Frontiers in public health · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
introductionDeficits in goal-directed behavior are common in individuals with Parkinson's disease (PD) and have been ascribed to apathy. In addition to apathy, individuals' beliefs in their competence (self-efficacy) and capacity to regulate emotions, thoughts, and actions (self-regulation) are critical skills for goal-directed behavior. We investigated these skills and their relationship to motor and non-motor symptoms in individuals with PD. We also examined the neural correlates of these skills using functional magnetic resonance imaging (fMRI).
methodsWe enrolled 35 subjects with mild PD (Hoehn and Yahr stage ≤2.5) and used the new general self-efficacy (NGSES) and self-regulation scales (SRS). We correlated the scores on these scales with measures of cognition, anxiety, depression, apathy, fatigue, quality of life, and disease burden using stepwise regression analyses. We collected resting-state fMRI data in a 3-Tesla scanner and computed the pairwise functional connectivity among nodes of major networks. We correlated the connectivity maps with the NGSES and SRS scores.
resultsOur PD cohort demonstrated intact NGSES and SRS scores compared with respective population data. These scores showed significant negative correlation with apathy and disease burden. Stronger connectivity in the salience network and decoupling from the default mode network supported self-efficacy and self-regulation.
conclusionsSelf-efficacy and self-regulation capacity seems preserved, but vulnerable to disease-related factors in individuals with mild PD. Educational programs cultivating this capacity could improve the coping skills of these individuals. Functional connectivity changes in salience and default mode networks may serve as neurobiological markers to demonstrate the effectiveness of such interventions.
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