ArticleiScience2021
Organization of feedback projections to mouse primary visual cortex.
Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- How perceptual learning rewires brain connectivity: lessons from the visual system in a top-down perspective.Frontiers in neural circuits · 2025Pooled it
- Excitatory and inhibitory networks diverge following early blindness.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Robust learning-driven structural and functional plasticity of spines in the mature mouse cortex: Robust learning-driven plasticity of spines in the mature cortex.bioRxiv : the preprint server for biology · 2026Article
- Neural Circuit with Top-Down Inhibitory Feedback Outperforms Optimal Bayesian Integration in Multisensory Integration.Neuroscience bulletin · 2026Article
- A shared multi-feature population code for sensory reliability across mouse visual cortex.bioRxiv : the preprint server for biology · 2026Article
- Cortical functional connectivity in mouse models of early blindness: enucleation vs. anophthalmia.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Anterior and posterior retrosplenial cortex form distinct visuospatial circuits in the mouse.Nature communications · 2026Article
- Characteristics and dynamical signatures of recurrent cortical circuits during context-dependent processing.bioRxiv : the preprint server for biology · 2026Article
- Cortical α-synuclein pathology induces cell autonomous neuronal hypoactivity and compensatory circuit changes in a model of early Lewy body dementia.bioRxiv : the preprint server for biology · 2025Article
- MeCP2 and non-CG DNA methylation stabilize the expression of long genes that distinguish closely related neuron types.Nature neuroscience · 2025Article
- Cortical circuits for cross-modal generalization.Nature communications · 2025Article
- An essential role for the latero-medial secondary visual cortex in the acquisition and retention of visual perceptual learning in mice.Nature communications · 2024Article
- Flexible neural population dynamics govern the speed and stability of sensory encoding in mouse visual cortex.Nature communications · 2024Article
- Auditory cortex conveys non-topographic sound localization signals to visual cortex.Nature communications · 2024Article
- A primary sensory cortical interareal feedforward inhibitory circuit for tacto-visual integration.Nature communications · 2024Article
- Interactions between rodent visual and spatial systems during navigation.Nature reviews. Neuroscience · 2023Review
- Recruitment of frontal sensory circuits during visual discrimination.Cell reports · 2022Article
- The spatiotemporal organization of experience dictates hippocampal involvement in primary visual cortical plasticity.Current biology : CB · 2021Article
- Representation of Contralateral Visual Space in the Human Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Top-down, context-dependent modulation of visual processing has been a topic of wide interest, including in mouse primary visual cortex (V1). However, the organization of feedback projections to V1 is relatively unknown. Here, we investigated inputs to mouse V1 by injecting retrograde tracers. We developed a software pipeline that maps labeled cell bodies to corresponding brain areas in the Allen Reference Atlas. We identified more than 24 brain areas that provide inputs to V1 and quantified the relative strength of their projections. We also assessed the organization of the projections, based on either the organization of cell bodies in the source area (topography) or the distribution of projections across V1 (bias). Projections from most higher visual and some nonvisual areas to V1 showed both topography and bias. Such organization of feedback projections to V1 suggests that parts of the visual field are differentially modulated by context, which can be ethologically relevant for a navigating animal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.