Evidence map›Paper›PMID 34113793›Full record

ReviewCardiovascular endocrinology & metabolism2021

Exercise, cancer and cardiovascular disease: what should clinicians advise?

Allison Zimmerman, Maria Isabel Camara Planek, Catherine Chu, Opeyemi Oyenusi, Agne Paner, Kerryn Reding, Jamario Skeete, Brian Clark, Tochi M Okwuosa

Open access · diamondAbstract readReview
In one paragraph

Review in Cardiovascular endocrinology & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Evaluation of Valid VOInternational journal of exercise science · 2025
    Article
  3. Review
  4. Article
  5. Factors Influencing the Decision of Individuals with Breast Cancer to Join an Exercise Oncology Trial.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Allison ZimmermanDepartment of Medicine, Rush University Medical Center.
Maria Isabel Camara PlanekDepartment of Medicine, Rush University Medical Center.
Catherine ChuRush Medical College, Rush University Medical Center.
Opeyemi OyenusiRush Medical College, Rush University Medical Center.
Agne PanerDivision of Hematology/Oncology, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois.
Kerryn RedingDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Jamario SkeeteDivision of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Brian ClarkDivision of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Tochi M OkwuosaDivision of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Rush University Medical Center · USFred Hutch Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is one of the leading causes of morbidity and mortality in persons with cancer. The elevated risk is thought to derive from the combination of cardiovascular risk factors and direct cardiotoxicity from cancer therapies. Exercise may be a potential strategy to counteract these toxicities and maintain cardiovascular reserve. In this article, we review the evidence for the potential cardioprotective effects of exercise training in cancer patients before, during, and following treatment. We also propose a patient-tailored approach for the development of targeted prescriptions based on individual exercise capacity and cardiovascular reserve.

Indexed as

cancercardioprotectioncardiotoxicitycardiovascular complicationscardiovascular disease preventionexercise

Identifiers

PMID34113793
PMCPMC8186519
OpenAlexW3083508594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.