ArticleOpen forum infectious diseases2021
Invasive
Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 30 citations in OpenAlex.
- Dental unit waterlines in Israel: evidence of widespread microbial contamination and a need for national regulation.Israel journal of health policy research · 2026Article
- Biweekly versus triweekly hydrogen peroxide shock treatment for controlling dental unit waterline contamination: a single-center pilot randomized clinical study.Frontiers in oral health · 2026Article
- Antimicrobial resistance in dental unit waterlines: a scoping review of microbial diversity, resistance patterns, and knowledge gaps.Frontiers in oral health · 2026Review
- Species Diversity of Nontuberculous Mycobacteria in Dental Unit Waterlines: Implications for Infection Control and Clinical Practice.Infection and drug resistance · 2026Article
- Validity and Applicability of Introducing a Healthcare-Associated Infection Surveillance System in Dental Hospitals in Korea Using the Delphi Technique.Healthcare (Basel, Switzerland) · 2025Article
- Mycobacterium farcinogenes-induced lymphadenitis in a pediatric patient: a case report.BMC infectious diseases · 2025Article
- The role of colony morphotype in shaping gene essentiality inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Successful treatment of macrolide-resistantASM case reports · 2025Article
- Antimicrobial Resistance in Oral Healthcare: A Growing Concern in Dentistry.Dentistry journal · 2025Review
- Review
- Periodic detection and disinfection maintenance of dental unit waterlines in dental simulation head model laboratories.Scientific reports · 2025Article
- Extrapulmonary Comparisons BetweenInfection and drug resistance · 2025Review
- Decoding water quality across urban and rural dental clinics: insights from an observational study.Frontiers in oral health · 2025Article
- Bacterial contamination of new dental unit waterlines and efficacy of shock disinfection.BMC microbiology · 2024Article
- Initial waterline contamination byMicrobiology spectrum · 2024Article
- Article
- CutaneousClinical, cosmetic and investigational dermatology · 2024Article
- The importance of biofilm contamination control for dental unit waterlines: a multicenter assessment of the microbiota diversity of biofilm in dental unit waterlines.Journal of oral microbiology · 2024Article
- Article
- Dental unit waterline testing practices: an 11-Year retrospective study.BMC oral health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background
methodsOdontogenic MAB infections occurred in patients following pulpotomy procedures at dental clinic A from 1 January to 6 September 2016. We identified confirmed and probable cases using culture data, imaging, pathology results, and surgical findings. Epidemiologic and clinical data including demographics, symptoms, laboratory findings, treatment regimens, and outcomes were extracted.
resultsOf 1082 at-risk patients, 71 case patients (22 confirmed; 49 probable) were identified. Median age was 6 years. Median symptom onset was 85 days postpulpotomy. Pain and/or swelling on admission occurred in 79%. On imaging, 49 of 70 had abnormalities of the mandible or maxilla, 13 of 70 had lymphadenopathy, and 19 of 68 had pulmonary nodules. Seventy were hospitalized (average of 8.5 days). Intravenous antibiotics were administered to 32 cases for a median length of 137 days. Clofazimine was administered to 29 patients as part of their multidrug regimen. Antibiotic treatment was associated with many adverse effects. Treated children showed evidence of jaw healing with resolved/improving pulmonary nodules at 1-year follow-up.
conclusionsThis is the largest outbreak of invasive MAB infections associated with a pediatric dental practice. While infections were indolent, patients suffered medical and surgical consequences of treatment, including permanent tooth loss. Identification of this outbreak led to a change in water standards for pediatric dental procedures in California. Enhanced national dental water quality standards are needed to prevent future outbreaks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.