Evidence map›Paper›PMID 34113633›Full record

ArticleFrontiers in medicine2021

An Adsorptive and Antioxidant Vaginal Gel Clears High-Risk HPV- and p16/Ki-67-Associated Abnormal Cytological Cervical Findings: A

Attila Louis Major, Ales Skřivánek, Etienne Marc Grandjean, Vladimír Dvořák, Tomáš Malík, Marek Pluta, Ivanna Mayboroda

Registry-linked trialOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05509413 (DEFLAGYN® Vaginal Gel and Spontaneous Remission and Regression of Unclear Cervical Smears and HPV High-risk Infections), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05509413 nacompletednot on this mapstarted 2022, after this paper: background citation

DEFLAGYN® Vaginal Gel and Spontaneous Remission and Regression of Unclear Cervical Smears and HPV High-risk Infections

TypeinterventionalSponsorRuhr University of BochumRan2022 to 2025Enrolled242ConditionsCervix Dysplasia, HPV InfectionArmsDEFLAGYN vaginal gel
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Medicina (Kaunas, Lithuania) · 2022
    Trial
  3. Observational
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Attila Louis MajorFemina Gynaecology Centre, Geneva, Switzerland.
Ales SkřivánekG-CENTRUM Olomouc, s.r.o., Olomouc, Czechia.
Etienne Marc GrandjeanPhidalsa Pharma Consultants, Geneva, Switzerland.
Vladimír DvořákCentrum ambulantní gynekologie a primární péče, s.r.o., Brno, Czechia.
Tomáš MalíkGyneko spol. s.r.o., Vsetin, Czechia.
Marek PlutaDepartment of Obstetrics and Gynaecology, Fakultní nemocnice v Motole (University Hospital Motol) Onkogynekologická a kolposkopická ambulance, Praha, Czechia.
Ivanna MayborodaDepartment of Obstetrics and Gynaecology, University Hospital of Geneva, Geneva, Switzerland.
University Hospital in Motol · CZUniversity Hospital of Geneva · CHUniversity of Fribourg · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

abnormal cervical smear findingsadsorptive and antioxidative vaginal gelcervical intraepithelial neoplasiahigh risk HPVp16/Ki-67 biomarkersilicon dioxidesodium selenitetumor environment

Identifiers

PMID34113633
PMCPMC8185015
OpenAlexW3164877009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.