Evidence map›Paper›PMID 34113347›Full record

ArticleFrontiers in immunology2021

A Virus-Specific Immune Rheostat in the Immunome of Patients Recovering From Mild COVID-19.

Joo Guan Yeo, Jing Yao Leong, Shi Huan Tay, Karen Donceras Nadua, Danielle E Anderson, Amanda Jin Mei Lim, Xiang Wen Ng, Su Li Poh, Dianyan Guo, Katherine Nay Yaung and 23 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Joo Guan YeoTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Jing Yao LeongTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Shi Huan TayTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Karen Donceras NaduaDuke-NUS Medical School, Singapore, Singapore.
Danielle E AndersonDuke-NUS Medical School, Singapore, Singapore.
Amanda Jin Mei LimTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Xiang Wen NgDepartment of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, Singapore.
Su Li PohTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Dianyan GuoTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Katherine Nay YaungTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Pavanish KumarTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Martin WasserTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Sharifah Nur HazirahTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Nursyuhadah SutamamTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Camillus Jian Hui ChuaTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Martin QuiDuke-NUS Medical School, Singapore, Singapore.
Randy FooDuke-NUS Medical School, Singapore, Singapore.
Akshamal Mihiranga GamageDuke-NUS Medical School, Singapore, Singapore.
Kee Thai YeoTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Lakshmi RamakrishnaTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Thaschawee ArkachaisriRheumatology and Immunology Service, Department of Pediatric Subspecialities, KK Women's and Children's Hospital, Singapore, Singapore.
Barnaby E YoungYong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore.
David Chien LyeYong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore.
Lin-Fa WangDuke-NUS Medical School, Singapore, Singapore.
Chia Yin ChongDuke-NUS Medical School, Singapore, Singapore.
Natalie Woon Hui TanDuke-NUS Medical School, Singapore, Singapore.
Jiahui LiDuke-NUS Medical School, Singapore, Singapore.
Kai-Qian KamDuke-NUS Medical School, Singapore, Singapore.
Florent GinhouxTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
Koh Cheng ThoonDuke-NUS Medical School, Singapore, Singapore.
Jerry Kok Yen ChanDuke-NUS Medical School, Singapore, Singapore.
Chee Fu YungDuke-NUS Medical School, Singapore, Singapore.
Salvatore AlbaniTranslational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An accurate depiction of the convalescent COVID-19 immunome will help delineate the immunological milieu crucial for disease resolution and protection. Using mass cytometry, we characterized the immune architecture in patients recovering from mild COVID-19. We identified a virus-specific immune rheostat composed of an effector T (T

Indexed as

AdolescentAdultCD4-Positive T-LymphocytesChildChild, PreschoolCOVID-19FemaleHumansMaleSARS-CoV-2Spike Glycoprotein, CoronavirusT Follicular Helper CellsT-Lymphocytes, RegulatoryYoung AdultSpike Glycoprotein, Coronavirusspike glycoprotein, SARS-CoVCOVID-19follicular helper T cellsmass cytometryregulatory T cellsSARS-CoV-2

Identifiers

PMID34113347
PMCPMC8185226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.