Evidence map›Paper›PMID 34113268›Full record

ArticleFrontiers in psychiatry2021

Genetic and Metabolite Variability in One-Carbon Metabolism Applied to an Insulin Resistance Model in Patients With Schizophrenia Receiving Atypical Antipsychotics.

Kristen M Ward, Kyle Burghardt, A Zarina Kraal, Andrew Jaeger, Larisa Yeomans, Cora McHugh, Alla Karnovsky, Kathleen A Stringer, Vicki L Ellingrod

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Frontiers in nutrition · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kristen M WardDepartment of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States.
Kyle BurghardtDepartment of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, United States.
A Zarina KraalDepartment of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States.
Andrew JaegerDepartment of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States.
Larisa YeomansNuclear Magnetic Resonance (NMR) Metabolomics Laboratory, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States.
Cora McHughNuclear Magnetic Resonance (NMR) Metabolomics Laboratory, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States.
Alla KarnovskyDepartment of Computational Medicine and Bioinformatics, School of Medicine, University of Michigan, Ann Arbor, MI, United States.
Kathleen A StringerDepartment of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States.
Vicki L EllingrodDepartment of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · USWayne State University · US

Funding

Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
PUBLIC HEALTH DEMONSTRATIONP60DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MYERS, MARTIN G · 1985 to 2012
$26.5M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
Institutional Career Development CoreKL2TR002241 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELLINGROD, VICKI L · 2017 to 2021
$6.9M
Folate Pharmacogenomics and Risk of Atypical Antipsychtoic Metabolic Side EffectsR01MH082784 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELLINGROD, VICKI L · 2008 to 2017
$4.0M
Translational Metabolomics in Critical CareR35GM136312 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KATHLEEN A STRINGER · 2020 to 2026
$2.8M
NCATS NIH HHS KL2 TR002241NCATS NIH HHS UL1 TR000433NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIDDK NIH HHS P60 DK020572NIGMS NIH HHS R35 GM136312NIMH NIH HHS R01 MH082784
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antipsychoticscardiovascular diseasefolateinsulin resistancemetabolomicsone-carbon metabolismpharmacogenomics

Identifiers

PMID34113268
PMCPMC8185170
OpenAlexW3165684873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.