Evidence map›Paper›PMID 34113202›Full record

ArticleJournal of blood medicine2021

Non Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation Patients Scheduled for Electrical Cardioversion: A Real-Life Propensity Score Matched Study.

Anna Rago, Enrica Pezzullo, Marco Malvezzi Caracciolo d'Aquino, Gabriella Scognamiglio, Valentina Maria Caso, Francesco Martone, Emilio Attena, Valentina Parisi, Antonio D'Onofrio, Paolo Golino and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of blood medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Anna RagoDepartment of Cardiology, Monaldi Hospital, Naples, Italy.
Enrica PezzulloDepartment of Cardiology, Monaldi Hospital, Naples, Italy.
Marco Malvezzi Caracciolo d'AquinoDepartment of Cardiology, Monaldi Hospital, Naples, Italy.
Gabriella ScognamiglioDepartment of Cardiology, Monaldi Hospital, Naples, Italy.
Valentina Maria CasoDepartment of Medical Translational Sciences, University of the Study of Campania "Luigi Vanvitelli", Naples, Italy.ORCID 0000-0002-7915-8366
Francesco MartoneClinical Biochemistry Unit, Monaldi Hospital, Naples, Italy.
Emilio AttenaDepartmental Unit of Electrophysiology, Monaldi Hospital, Naples, Italy.
Valentina ParisiDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.
Antonio D'OnofrioDepartmental Unit of Electrophysiology, Monaldi Hospital, Naples, Italy.
Paolo GolinoDepartment of Cardiology, Monaldi Hospital, Naples, Italy.
Gerardo NigroDepartment of Cardiology, Monaldi Hospital, Naples, Italy.ORCID 0000-0003-1776-8449
Vincenzo RussoDepartment of Cardiology, Monaldi Hospital, Naples, Italy.
Ospedale Monaldi · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of the present study was to assess the safety and effectiveness of non-vitamin K antagonist oral anticoagulants (NOACs) versus vitamin K antagonists (VKAs) in atrial fibrillation (AF) patients undergoing electrical cardioversion (EC).

methodsA propensity score-matched analysis was performed in order to identify two homogeneous groups including AF patients on NOACs and VKAs treatment scheduled for EC. The primary safety endpoint was major bleeding. The composite of stroke, transient ischemic attack (TIA) and systemic embolism (SE) was the primary effectiveness endpoint. The discontinuation rate of anticoagulant therapy was assessed.

resultsA total of 495 AF patients on NOACs therapy and scheduled for EC were compared to 495 VKAs recipients. No statistically significant differences in the incidence of both major bleeding (1.01% versus 1.4%;

conclusionWe showed a safe and effective clinical profile of NOACs among AF patients scheduled for electrical cardioversion in real-life setting. Patients on NOACs therapy showed a lower discontinuation rate compared to those on VKAs.

Indexed as

atrial fibrillationdiscontinuation rateelectrical cardioversionnon-vitamin K antagonist oral anticoagulantstransesophageal echocardiogramvitamin K antagonists

Identifiers

PMID34113202
PMCPMC8187032
OpenAlexW3169036187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.