Evidence map›Paper›PMID 34113140›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021

Relationship Between Vitamin D Status and the Relevant Parameters of Glucose in Patients with Type 2 Diabetes.

Thanh Tung Tran Huu, Huu Dang Tran, Thua Nguyen Tran, Bui Bao Hoang

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. The Relationship Between Triglyceride Glucose Index and Vitamin D in Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Thanh Tung Tran HuuHue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam.ORCID 0000-0003-2583-6851
Huu Dang TranDepartment of Internal Medicine, Hue University of Medicine and Pharmacy, Hue City, Vietnam.
Thua Nguyen TranDepartment of General Internal Medicine and Geriatrics, Hue Central Hospital, Hue City, Vietnam.
Bui Bao HoangDepartment of Internal Medicine, Hue University of Medicine and Pharmacy, Hue City, Vietnam.
Hue University · VNHue Central Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionClarifying the prevalence of vitamin D deficiency in diabetic patients, and the relationship between vitamin D concentration and insulin resistance, fasting plasma glucose, and HbA1C in patients in Hue City, Vietnam.

methodsA cross-sectional study on 110 diabetic patients examined at Hue Central Hospital and Hue University of Medicine and Pharmacy Hospital. These patients were collected venous blood sampling, and the 25(OH)D test, fasting plasma glucose test, fasting insulin test, HOMA-IR and QUICKI calculation.

resultsVitamin D deficiency and insufficiency prevalence were 51.8%. The average concentration of 25(OH)D (ng/mL) was 30.67 ± 8.55; this concentration in fasting glucose level ≤8 mmol/l group and >8 mmol/l group was 32.08 ± 9.26 and 28.55±6.91 (p = 0.033); it was 32.95 ± 8.58 and 28.97 ± 8.17 in HOMA-IR ≤3.5 and HOMA-IR >3.5 group, (p = 0.015); in QUICKI ≤0.32 group, it was 29.16 ± 8.12; in QUICKI >0.32 group, it was 32.85 ± 8.76 (p = 0.025). Patients with an ideal exercise level have higher average levels of 25(OH)D (32.11±8.62 vs 26.83±7.16, p=0.003). The average levels of 25(OH)D in male patients are higher than in female patients (33.47±0.08 vs 29.01±8.43, p=0.008). Vitamin D deficiency and insufficiency prevalence in patients with HOMA-IR ≤3.5 and QUICKI >0.32 were 36.2% and 37.8%, whereas in those with HOMA-IR >3.5 and QUICKI ≤0.32 they were 63.5% and 61.5% (p = 0.007 and 0.02, respectively). 25(OH)D is negative correlation with fasting glucose level and HOMA-IR, with r = -0.229 and -0.192, respectively (p = 0.016 and 0.045); 25(OH)D was positively correlated with QUICKI, with r = 0.235, p = 0.008.

conclusionPatients who have better glucose-related parameters, such as fasting blood sugar, HOMA-IR and QUICKI, have a better vitamin D status. Some blood sugar-related factors, such as exercise level and sex, are related to vitamin D status.

Indexed as

diabetesHbA1Cinsulin resistancevitamin D

Identifiers

PMID34113140
PMCPMC8184150
OpenAlexW3168898482

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.