Evidence map›Paper›PMID 34113088›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2021

Characterization of COPD Admissions During the First COVID-19 Outbreak.

Borja G Cosio, Hanaa Shafiek, Nuria Toledo-Pons, Amanda Iglesias, Margalida Barcelo, Cristina Represas-Represas, Lorena Comeche, Pablo Catalan, Alberto Fernandez-Villar, Jose Luis Lopez-Campos and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Clinical outcomes among hospitalized US adults with asthma or chronic obstructive pulmonary disease, with or without COVID-19.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Borja G CosioRespiratory Medicine, Hospital Universitario Son Espases-IdISBa, Palma de Mallorca, Spain.ORCID 0000-0002-6388-8209
Hanaa ShafiekRespiratory Medicine, Hospital Universitario Son Espases-IdISBa, Palma de Mallorca, Spain.ORCID 0000-0002-4716-4809
Nuria Toledo-PonsRespiratory Medicine, Hospital Universitario Son Espases-IdISBa, Palma de Mallorca, Spain.ORCID 0000-0002-2599-4473
Amanda IglesiasRespiratory Medicine, Hospital Universitario Son Espases-IdISBa, Palma de Mallorca, Spain.ORCID 0000-0003-2600-351X
Margalida BarceloRespiratory Medicine, Hospital Universitario Son Espases-IdISBa, Palma de Mallorca, Spain.
Cristina Represas-RepresasRespiratory Medicine, Hospital Alvaro Cunqueiro, Vigo, Spain.
Lorena ComecheRespiratory Medicine, Hospital Universitario Quironsalud Madrid, Madrid, Spain.
Pablo CatalanRespiratory Medicine, Hospital General de Castellón, Castellón, Spain.
Alberto Fernandez-VillarRespiratory Medicine, Hospital Alvaro Cunqueiro, Vigo, Spain.
Jose Luis Lopez-CamposRespiratory Medicine, Hospital Virgen del Rocio-CIBERES, Sevilla, Spain.ORCID 0000-0003-1703-1367
Jose Echave-SustaetaRespiratory Medicine, Hospital Universitario Quironsalud Madrid, Madrid, Spain.
Juan Jose Soler-CatalunaRespiratory medicine, Hospital Arnau de Vilanova-CIBERES, Valencia, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESHealth Research Institute of the Balearic Islands · ESHospital Universitario Quirónsalud Madrid · ESUniversity Hospital Complex Of Vigo · ESHospital Arnau de Vilanova · ESHospital General Universitari de Castelló · ESHospital Universitario Virgen del Rocío · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Exacerbations of COPD (ECOPD) are a frequent cause of hospitalization that seemed to ameliorate during the COVID outbreak. We aimed to evaluate the clinical characteristics of COPD-related hospital admissions and mortality in relation to the presence of COVID-19. Patients and Methods: We conducted a case-control study of patients admitted in four teaching hospitals throughout Spain between March 15 and April 30, 2020. Hospital admissions of respiratory cause with and without PCR-proven SARS-CoV-2 infection in patients with COPD were evaluated. Baseline and episode-related clinical characteristics were analyzed. Logistic regression analysis was performed to evaluate the risk for mortality. Results: During the study period, 2101 patients were admitted for respiratory worsening, 1200 (57.1%) with COVID-19. A total of 228 (10.8%) were admitted due to COPD worsening, of whom 52 (22.8%) tested positive for COVID-19. COPD patients with COVID-19, when compared to those without COVID-19, were more frequently males with better lung function (FEV Conclusion: Hospitalizations for ECOPD without COVID-19 were more frequent than COPD with COVID-19 during the first outbreak, but the latter were associated with higher mortality and low eosinophil counts that warrant further analysis.

Indexed as

COVID-19Pulmonary Disease, Chronic ObstructiveCase-Control StudiesDisease OutbreaksHospitalizationHumansMaleSARS-CoV-2SpainCOPD exacerbationhospitalizationinhaled corticosteroidsmortality

Identifiers

PMID34113088
PMCPMC8184145
OpenAlexW3168341464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.