ArticleNature nanotechnology2021
X-ray-activated persistent luminescence nanomaterials for NIR-II imaging.
Article in Nature nanotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.
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Who cites it
118 citing papers in PubMed.
- Antenna Effect for Enhanced Near-Infrared Luminescence in Lanthanide-Doped Nanoparticles: Mechanisms, Strategies, and Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Tailoring Photonic Landscape: Nanoengineering Empowers NIR-II Lanthanide Luminescence for Versatile Biomedical Applications.Small methods · 2026Review
- Synthesis of radioafterglow nanoprobes for deep-tissue imaging of hydrogen peroxide.Nature protocols · 2026Review
- Ambient Light-Activatable Luminescent Particle-Embedded Conformal Patch for Photochemical Tissue Bonding and Photobiomodulated Healing.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Mesoscale ordered assembly of ErNature communications · 2026Article
- Tunable persistent luminescence nanoparticles for profiling bacterial extracellular azoreductase activity and antibiotic susceptibility.Analytical and bioanalytical chemistry · 2026Article
- Radioisotope-mimetic molecular afterglow probe for downregulated cancer biomarker imaging.Nature materials · 2026Article
- A renally clearable tumor-targeted probe enabling functional delineation of tumor margins by NIR-II fluorescence lifetime imaging.Materials today. Bio · 2026Article
- Machine-learning guided engineering of MoNature communications · 2026Article
- Multifunctional fiber-optic theranostic probe for closed-loop tumor photothermal therapy.Light, science & applications · 2026Article
- Synthesis of Samarium-incorporated X-ray-sensitive nanoparticles and hydrogels: Diverse applications in radiation monitoring and dynamic information display.Smart molecules : open access · 2026Article
- Autofluorescence-free ratiometric temperature monitoring with multiple emissive persistent luminescent nanothermometers.Analytical and bioanalytical chemistry · 2026Article
- In vivo ultrasound-induced luminescence imaging via trianthracene derivatives nanomaterials.Nature protocols · 2026Review
- Synthesis of transition metal-sensitized lanthanide near-infrared luminescent nanoparticles.Nature protocols · 2026Review
- Boltzmann luminescent nanothermometry: mechanistic criteria and predictive design of thermally coupled levels.Light, science & applications · 2026Article
- X-ray preactivated reversible persistent luminescence enables photodynamic immunotherapy of deep tumors.Nature communications · 2026Article
- Organic small-molecule NIR-II fluorophores for tumor phototheranostics.Light, science & applications · 2026Review
- Anapole-state-enhanced 2D chiral photodetector operating in the near-infrared second window.Nature communications · 2026Article
- Tough transparent glass ceramics for multi-mode programmable dynamic tunable persistent luminescence via phase engineering.Nature communications · 2026Article
- Efficient multicolor X-ray excited persistent luminescence enabled by Gd-mediated trap clusters.Nature communications · 2026Article
58 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Persistent luminescence is not affected by background autofluorescence, and thus holds the promise of high-contrast bioimaging. However, at present, persistent luminescent materials for in vivo imaging are mainly bulk crystals characterized by a non-uniform size and morphology, inaccessible core-shell structures and short emission wavelengths. Here we report a series of X-ray-activated, lanthanide-doped nanoparticles with an extended emission lifetime in the second near-infrared window (NIR-II, 1,000-1,700 nm). Core-shell engineering enables a tunable NIR-II persistent luminescence, which outperforms NIR-II fluorescence in signal-to-noise ratios and the accuracy of in vivo multiplexed encoding and multilevel encryption, as well as in resolving mouse abdominal vessels, tumours and ureters in deep tissue (~2-4 mm), with up to fourfold higher signal-to-noise ratios and a threefold greater sharpness. These rationally designed nanoparticles also allow the high-contrast multiplexed imaging of viscera and multimodal NIR-II persistent luminescence-magnetic resonance-positron emission tomography imaging of murine tumours.
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