Evidence map›Paper›PMID 34112965›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2021

Clinical risk models for preterm birth less than 28 weeks and less than 32 weeks of gestation using a large retrospective cohort.

Reza Arabi Belaghi, Joseph Beyene, Sarah D McDonald

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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Reza Arabi BelaghiDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.ORCID http://orcid.org/0000-0002-6989-9267
Joseph BeyeneDepartment of Health Research Methods, Evidence & Impact, McMaster University, Hamilton, Ontario, Canada.
Sarah D McDonaldDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada. mcdonals@mcmaster.ca.ORCID http://orcid.org/0000-0002-4461-2178

Funding

CIHR 151520CIHR 950-229920
6 · The paper itself

Abstract

objectiveTo develop risk prediction models for singleton preterm birth (PTB) < 28 weeks and <32 weeks.

methodsUsing a retrospective cohort of 267,226 singleton births in Ontario hospitals, we included variables from the first and second trimester in multivariable logistic regression models to predict overall and spontaneous PTB < 28 weeks and <32 weeks.

resultsDuring the first trimester, the area under the curve (AUC) for prediction of PTB < 28 weeks for nulliparous and multiparous women was 68.5% (95% CI: 63.5-73.6%) and 73.4% (68.6-78.2%), respectively, while for PTB < 32 weeks it was 68.9% (65.5-72.3%) and 75.5% (72.3-78.7%), respectively. AUCs for second-trimester models were 72.4% (95% CI: 69.7-75.1%) and 78.2% (95% CI: 75.8-80.5%), respectively, in nulliparous and multiparous women. Predicted probabilities were well-calibrated within a wide range around expected base prevalence for the study outcomes.

conclusionsOur prediction models generated acceptable AUCs for PTB < 28 weeks and <32 weeks with good calibration during the first and second trimester.

Indexed as

Premature BirthCohort StudiesFemaleHumansInfant, NewbornPregnancyPregnancy Trimester, FirstPregnancy Trimester, SecondRetrospective StudiesRisk Factors

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.