ArticleScientific reports2021
Diversity and interactions among triatomine bugs, their blood feeding sources, gut microbiota and Trypanosoma cruzi in the Sierra Nevada de Santa Marta in Colombia.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Triatomine Fauna and Natural Infection by Trypanosoma (Schizotrypanum) cruzi (Kinetoplastea: Trypanosomatidae) in the Caribbean Region of Panama, Colombia, and Venezuela: A Systematic Review.Neotropical entomology · 2025Pooled it
- Who Feeds theMicroorganisms · 2026Article
- Unveiling the ecology and spatial dynamics of Trypanosoma cruzi, its DTUs and Triatoma vitticeps in the Atlantic Forest of south-eastern Espírito Santo State, Brazil.PLoS neglected tropical diseases · 2026Article
- Ecological origin and naturalCurrent research in parasitology & vector-borne diseases · 2026Article
- Coinfection by multipleMicrobiology and molecular biology reviews : MMBR · 2025Review
- Review
- Interaction ofMicroorganisms · 2024Review
- Intra-hostMicrobiology spectrum · 2023Article
- Humans as blood-feeding sources in sylvatic triatomines of Chile unveiled by next-generation sequencing.Parasites & vectors · 2023Article
- Article
- Estimating the genetic structure of Triatoma dimidiata (Hemiptera: Reduviidae) and the transmission dynamics of Trypanosoma cruzi in Boyacá, eastern Colombia.PLoS neglected tropical diseases · 2022Article
- Towards environmental detection of Chagas disease vectors and pathogen.Scientific reports · 2022Article
- Exposure to Trypanosoma parasites induces changes in the microbiome of the Chagas disease vector Rhodnius prolixus.Microbiome · 2022Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Chagas disease remains a major neglected disease in Colombia. We aimed to characterize Trypanosoma cruzi transmission networks in the Sierra Nevada de Santa Marta (SNSM) region, to shed light on disease ecology and help optimize control strategies. Triatomines were collected in rural communities and analyzed for blood feeding sources, parasite diversity and gut microbiota composition through a metagenomic and deep sequencing approach. Triatoma dimidiata predominated, followed by Rhodnius prolixus, Triatoma maculata, Rhodnius pallescens, Panstrongylus geniculatus and Eratyrus cuspidatus. Twenty-two species were identified as blood sources, resulting in an integrated transmission network with extensive connectivity among sylvatic and domestic host species. Only TcI parasites were detected, predominantly from TcIb but TcIa was also reported. The close relatedness of T. cruzi strains further supported the lack of separate transmission cycles according to habitats or triatomine species. Triatomine microbiota varied according to species, developmental stage and T. cruzi infection. Bacterial families correlated with the presence/absence of T. cruzi were identified. In conclusion, we identified a domestic transmission cycle encompassing multiple vector species and tightly connected with sylvatic hosts in the SNSM region, rather than an isolated domestic transmission cycle. Therefore, integrated interventions targeting all vector species and their contact with humans should be considered.
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