Evidence map›Paper›PMID 34112687›Full record

ArticleScience (New York, N.Y.)2021

Inhibitors of bacterial H

Konstantin Shatalin, Ashok Nuthanakanti, Abhishek Kaushik, Dmitry Shishov, Alla Peselis, Ilya Shamovsky, Bibhusita Pani, Mirna Lechpammer, Nikita Vasilyev, Elena Shatalina and 5 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed
23.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 235 citations in OpenAlex.

  1. Dismantling the eDNA-mediated HBioactive materials · 2027
    Article
  2. Review
  3. Gut microbes · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  10. Article
  11. The potential role of HNature communications · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Konstantin Shatalin *Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-8653-2355
Ashok Nuthanakanti *Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-0105-3430
Abhishek KaushikDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-0637-7776
Dmitry ShishovGero LLC, Moscow, Russia.ORCID 0000-0001-9503-3822
Alla PeselisDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
Ilya ShamovskyDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-5590-3165
Bibhusita PaniDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
Mirna LechpammerDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-6235-6227
Nikita VasilyevDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-9918-5735
Elena ShatalinaDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
Dmitri RebatchoukEllyris LLC, Union, NJ 07083, USA.
Alexander MironovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Moscow 119991, Russia.ORCID 0000-0003-3914-1380
Peter FedichevGero LLC, Moscow, Russia.
Alexander SerganovDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-8328-9310
Evgeny NudlerDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA. evgeny.nudler@nyulangone.org.ORCID 0000-0002-8811-3071
New York University · USEngelhardt Institute of Molecular Biology · RUHoward Hughes Medical Institute · USKean University · US

Funding

X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Sean McSweeney · 2019 to 2026
$38.6M
User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI MALCOLM S. CAPEL · 2018 to 2026
$34.2M
Pixel Array Detector for Macromolecular CrystallographyS10OD021527 · OD · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2016 to 2016
$2.0M
Pixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8M
NCRR NIH HHS S10 RR029205NIGMS NIH HHS P30 GM124165NIGMS NIH HHS P30 GM133893NIH HHS S10 OD021527
6 · The paper itself

Abstract

Emergent resistance to all clinical antibiotics calls for the next generation of therapeutics. Here we report an effective antimicrobial strategy targeting the bacterial hydrogen sulfide (H

Indexed as

AnimalsAnti-Bacterial AgentsBiofilmsCrystallography, X-RayCystathionine gamma-LyaseDrug DiscoveryDrug Resistance, BacterialDrug SynergismDrug ToleranceEnzyme InhibitorsHydrogen SulfideMiceMicrobial Sensitivity TestsModels, MolecularMolecular Docking SimulationMolecular StructureAnti-Bacterial AgentsCystathionine gamma-LyaseEnzyme InhibitorsHydrogen SulfideSmall Molecule Libraries

Identifiers

PMID34112687
PMCPMC10723041
OpenAlexW3170819454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.