SynthesisWorld journal of emergency surgery : WJES2021
Surgical site infection prevention and management in immunocompromised patients: a systematic review of the literature.
Synthesis in World journal of emergency surgery : WJES, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Effects of preoperative recombinant Interleukin 2-based immunomodulation on outcome after gastrointestinal cancer surgery: a systematic review and meta-analysis.British journal of cancer · 2026Pooled it
- Reported Postoperative Surgical Site Infections in Tertiary Care Hospitals, Systematic Review of Recent Literature.Current drug safety · 2025Pooled it
- Capsulectomy at Explant: Rethinking Spinal Cord Stimulator Infected Generator Pocket Management in the Immunocompromised-A Case Series.Pain practice : the official journal of World Institute of Pain · 2026Article
- Article
- Clinical and Postoperative Applications of Manuka Honey in Wound Healing: An Evidence-Based Review.International wound journal · 2026Review
- Wide Awake Facial Reconstruction: A Literature Review, Cost Analysis, and Practical Guide.Plastic and reconstructive surgery. Global open · 2026Article
- Two Multidrug-ResistantPathogens (Basel, Switzerland) · 2026Article
- Hernia mesh repair in immunocompromised patients: a comprehensive review.Hernia : the journal of hernias and abdominal wall surgery · 2026Review
- A cross-specialty, evidence-based Delphi consensus of a care bundle to reduce surgical site infections.International journal of surgery (London, England) · 2026Article
- Impact of osteosarcopenia in older people on prognosis following major surgery: a scoping review.PeerJ · 2026Article
- Surgical Site Infection Prevention Research: A Bibliometric Analysis of the Top 50 Highly Cited Articles.Cureus · 2026Review
- Care of the immunocompromised cancer patient in the perioperative period: Narrative review.Indian journal of anaesthesia · 2025Review
- Postoperative outcomes in transplant patients undergoing ventral hernia repair.Surgical endoscopy · 2025Article
- Modulation of Surgical Site Infection Risk in Spinal and Thoracic Surgeries Through Operative Parameters: A Narrative Review.Journal of clinical medicine · 2025Review
- An Unusual Presentation of Dermatofibroma with Ulcer: A Case Report.Dermatopathology (Basel, Switzerland) · 2025Article
- Article
- Antibiotics in Mucogingival Surgery for Recession Treatment: A Narrative Review.Antibiotics (Basel, Switzerland) · 2025Review
- Understanding the anatomical basis of anorectal fistulas and their surgical management: exploring different types for enhanced precision and safety.Surgery today · 2025Review
- Impact of immunosuppression medication management on short-term complications following sleeve gastrectomy.Surgical endoscopy · 2025Article
- Optimizing risk management for post-amputation wound complications in diabetic patients: Focus on glycemic and immunosuppressive control.World journal of diabetes · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 8 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImmunocompromised patients are at higher risk of surgical site infection and wound complications. However, optimal management in the perioperative period is not well established. Present systematic review aims to analyse existing strategies and interventions to prevent and manage surgical site infections and other wound complications in immunocompromised patients.
methodsA systematic review of the literature was conducted.
resultsLiterature review shows that partial skin closure is effective to reduce SSI in this population. There is not sufficient evidence to definitively suggest in favour of prophylactic negative pressure wound therapy. The use of mammalian target of rapamycin (mTOR) and calcineurin inhibitors (CNI) in transplanted patient needing ad emergent or undeferrable abdominal surgical procedure must be carefully and multidisciplinary evaluated. The role of antibiotic prophylaxis in transplanted patients needs to be assessed.
conclusionStrict adherence to SSI infection preventing bundles must be implemented worldwide especially in immunocompromised patients. Lastly, it is necessary to elaborate a more widely approved definition of immunocompromised state. Without such shared definition, it will be hard to elaborate the needed methodologically correct studies for this fragile population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.