Evidence map›Paper›PMID 34112173›Full record

ArticleJournal of nanobiotechnology2021

Silicon dioxide nanoparticles induced neurobehavioral impairments by disrupting microbiota-gut-brain axis.

Jun Diao, Yinyin Xia, Xuejun Jiang, Jingfu Qiu, Shuqun Cheng, Junhao Su, Xinhao Duan, Min Gao, Xia Qin, Jun Zhang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Jun Diao *Department of Occupational and Environmental Health, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Yinyin Xia *Department of Occupational and Environmental Health, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Xuejun Jiang *Center of Experimental Teaching for Public Health, Experimental Teaching and Management Center, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Jingfu QiuDepartment of Health Laboratory Technology, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Shuqun ChengDepartment of Occupational and Environmental Health, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Junhao SuDepartment of Health Laboratory Technology, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Xinhao DuanDepartment of Health Laboratory Technology, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Min GaoDepartment of Health Laboratory Technology, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Xia QinDepartment of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Jun ZhangMolecular Biology Laboratory of Respiratory Disease, Institute of Life Sciences, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Jingchuan FanMolecular Biology Laboratory of Respiratory Disease, Institute of Life Sciences, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Zhen ZouMolecular Biology Laboratory of Respiratory Disease, Institute of Life Sciences, Chongqing Medical University, Chongqing, 400016, People's Republic of China. zouzhen@cqmu.edu.cn.ORCID http://orcid.org/0000-0002-1651-591X
Chengzhi ChenDepartment of Occupational and Environmental Health, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China. chengzhichen@cqmu.edu.cn.ORCID http://orcid.org/0000-0002-1087-4911
Chongqing Medical University · CNChongqing Public Health Medical Center · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

National Natural Science Foundation of China 81602820National Natural Science Foundation of China 81703187National Natural Science Foundation of China 81903358
6 · The paper itself

Abstract

backgroundSilicon dioxide nanoparticles (SiO

methodsIn current study, the young mice were orally administrated with vehicle or SiO

resultsOur results demonstrated that SiO

conclusionThis study provides a novel idea that the SiO

Indexed as

AnimalsBrainGastrointestinal MicrobiomeInflammationLiverMaleMiceMice, Inbred C57BLNanoparticlesNeuronsSilicon DioxideSilicon DioxideGut–brain axisGut microbiotaNeurobehavioral impairmentsSilicon dioxide nanoparticles

Identifiers

PMID34112173
PMCPMC8194163
OpenAlexW3171363450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.