Evidence map›Paper›PMID 34111982›Full record

Observational studyThe British journal of radiology2021

Saturation recovery-prepared magnetic resonance angiography for assessment of left atrial and esophageal anatomy.

Johannes Siebermair, Eugene G Kholmovski, Douglas Sheffer, Joyce Schroeder, Leif Jensen, Mobin Kheirkhahan, Alex A Baher, Majd M Ibrahim, Theresa Reiter, Tienush Rassaf and 4 more

Open access · bronzeAbstract readObservational StudyValidation Study
In one paragraph

Observational study in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Johannes SiebermairDepartment of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Essen Medical School, University Duisburg-Essen, Essen, Germany.ORCID https://orcid.org/0000-0003-4134-3256
Eugene G KholmovskiComprehensive Arrhythmia Research & Management Center, University of Utah, Salt Lake City, UT, USA.
Douglas ShefferComprehensive Arrhythmia Research & Management Center, University of Utah, Salt Lake City, UT, USA.
Joyce SchroederUCAIR, Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
Leif JensenUCAIR, Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
Mobin KheirkhahanComprehensive Arrhythmia Research & Management Center, University of Utah, Salt Lake City, UT, USA.
Alex A BaherComprehensive Arrhythmia Research & Management Center, University of Utah, Salt Lake City, UT, USA.
Majd M IbrahimDivision of Cardiovascular Medicine, University of Utah, Salt Lake City, UT, USA.
Theresa ReiterDepartment of Internal Medicine, Cardiology, University Hospital Wuerzburg, Würzburg, Germany.
Tienush RassafDepartment of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Essen Medical School, University Duisburg-Essen, Essen, Germany.
Reza WakiliDepartment of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Essen Medical School, University Duisburg-Essen, Essen, Germany.
Nassir F MarroucheComprehensive Arrhythmia Research & Management Center, University of Utah, Salt Lake City, UT, USA.
Christopher J McGannComprehensive Arrhythmia Research & Management Center, University of Utah, Salt Lake City, UT, USA.
Brent D WilsonComprehensive Arrhythmia Research & Management Center, University of Utah, Salt Lake City, UT, USA.
University of Utah · USGerman Centre for Cardiovascular Research · DETulane University · USUniversitätsklinikum Würzburg · DEWest German Heart and Vascular Center Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMagnetic resonance angiography (MRA) has been established as an important imaging method in cardiac ablation procedures. In pulmonary vein (PV) isolation procedures, MRA has the potential to minimize the risk of severe complications, such as atrio-esophageal fistula, by providing detailed information on esophageal position relatively to cardiac structures. However, traditional non-gated, first-pass (FP) MRA approaches have several limitations, such as long breath-holds, non-uniform signal intensity throughout the left atrium (LA), and poor esophageal visualization. The aim of this observational study was to validate a respiratory-navigated, ECG-gated (EC), saturation recovery-prepared MRA technique for simultaneous imaging of LA, LA appendage, PVs, esophagus, and adjacent anatomical structures.

methodsBefore PVI, 106 consecutive patients with a history of AF underwent either conventional FP-MRA (

resultsEC-MRA demonstrated significantly better image quality than FP-MRA in every quality category. Esophageal visibility using the new MRA technique was markedly better than with the conventional FP-MRA technique (median 3.5 [IQR 1]

conclusionOur ECG-gated, respiratory-navigated, saturation recovery-prepared MRA technique provides significantly better image quality and esophageal visibility than the established non-gated, breath-holding FP-MRA. Image quality of EC-MRA technique has the additional advantage of being unaffected by heart rate. ADVANCES IN KNOWLEDGE: Detailed information of cardiac anatomy has the potential to minimize the risk of severe complications and improve success rates in invasive electrophysiological studies. Our novel ECG-gated, respiratory-navigated, saturation recovery-prepared MRA technique provides significantly better image quality of LA and esophageal structures than the traditional first-pass algorithm. This new MRA technique is robust to arrhythmia (tachycardic, irregular heart rates) frequently observed in AF patients.

Indexed as

Atrial AppendageAtrial FibrillationBreath HoldingCardiac-Gated Imaging TechniquesContrast MediaEsophagusFemaleHeart AtriaHumansMagnetic Resonance AngiographyMaleMeglumineMiddle AgedOrganometallic CompoundsPulmonary VeinsRespiratory-Gated Imaging TechniquesContrast Mediagadobenic acidMeglumineOrganometallic Compounds

Identifiers

PMID34111982
PMCPMC8248198
OpenAlexW3170935392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.