Evidence map›Paper›PMID 34111976›Full record

ArticleThe British journal of radiology2021

A comparison of the fusion model of deep learning neural networks with human observation for lung nodule detection and classification.

Ayşegül Gürsoy Çoruh, Bülent Yenigün, Çağlar Uzun, Yusuf Kahya, Emre Utkan Büyükceran, Atilla Elhan, Kaan Orhan, Ayten Kayı Cangır

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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  5. Current trends and future directions of artificial intelligence in lung cancer diagnosis.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ayşegül Gürsoy ÇoruhDepartment of Radiology, School of Medicine, Ankara University, Ankara, Turkey.
Bülent YenigünDepartment of Thoracic Surgery, School of Medicine, Ankara University, Ankara, Turkey.
Çağlar UzunDepartment of Radiology, School of Medicine, Ankara University, Ankara, Turkey.
Yusuf KahyaDepartment of Thoracic Surgery, School of Medicine, Ankara University, Ankara, Turkey.
Emre Utkan BüyükceranDepartment of Radiology, School of Medicine, Ankara University, Ankara, Turkey.
Atilla ElhanDepartment of Biostatistics, School of Medicine, Ankara University, Ankara, Turkey.
Kaan OrhanDentomaxillofacial Radiology, Ankara University, Faculty of Dentistry and Ankara University Medical Design Application and Research Center, Ankara, Turkey.
Ayten Kayı CangırDepartment of Thoracic Surgery, School of Medicine, Ankara University, Ankara, Turkey.
Ankara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the diagnostic performance of a newly developed artificial intelligence (AI) algorithm derived from the fusion of convolution neural networks (CNN) versus human observers in the estimation of malignancy risk in pulmonary nodules.

methodsThe study population consists of 158 nodules from 158 patients. All nodules (81 benign and 77 malignant) were determined to be malignant or benign by a radiologist based on pathologic assessment and/or follow-up imaging. Two radiologists and an AI platform analyzed the nodules based on the Lung-RADS classification. The two observers also noted the size, location, and morphologic features of the nodules. An intraclass correlation coefficient was calculated for both observers and the AI; ROC curve analysis was performed to determine diagnostic performances.

resultsNodule size, presence of spiculation, and presence of fat were significantly different between the malignant and benign nodules (

conclusionThe performance of the fusion AI algorithm in estimating the risk of malignancy was slightly lower than the performance of the observers. Fusion AI algorithms might be applied in an assisting role, especially for inexperienced radiologists. ADVANCES IN KNOWLEDGE: In this study, we proposed a fusion model using four state-of-art object detectors for lung nodule detection and discrimination. The use of fusion of deep learning neural networks might be used in a supportive role for radiologists when interpreting lung nodule discrimination.

Indexed as

Deep LearningAdultAgedAged, 80 and overContrast MediaFemaleHumansImaging, Three-DimensionalIohexolLung NeoplasmsMaleMiddle AgedObservationRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedContrast MediaIohexol

Identifiers

PMID34111976
PMCPMC8248221
OpenAlexW3169573018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.