Evidence map›Paper›PMID 34111910›Full record

ReviewJournal of pathology and translational medicine2021

Distinctive morphological and molecular features of urothelial carcinoma with an inverted growth pattern.

Francesca Sanguedolce, Beppe Calò, Marco Chirico, Ugo Falagario, Gian Maria Busetto, Magda Zanelli, Alessandra Bisagni, Maurizio Zizzo, Stefano Ascani, Giuseppe Carrieri and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of pathology and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesca SanguedolcePathology Unit, University of Foggia, Foggia, Italy.
Beppe CalòUrology Unit, University of Foggia, Bonomo Teaching Hospital, Foggia, Italy.
Marco ChiricoUrology and Renal Transplantation Unit, University of Foggia, Foggia, Italy.
Ugo FalagarioUrology and Renal Transplantation Unit, University of Foggia, Foggia, Italy.
Gian Maria BusettoUrology and Renal Transplantation Unit, University of Foggia, Foggia, Italy.
Magda ZanelliPathology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Alessandra BisagniPathology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Maurizio ZizzoSurgical Oncology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Stefano AscaniPathology Unit, Azienda Ospedaliera S. Maria di Terni, University of Perugia, Terni, Italy.
Giuseppe CarrieriUrology and Renal Transplantation Unit, University of Foggia, Foggia, Italy.
Luigi CormioUrology Unit, University of Foggia, Bonomo Teaching Hospital, Foggia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urothelial carcinoma with an inverted growth pattern (UC-IGP) is a peculiar entity within the spectrum of urothelial lesions. While efforts have been made over the last few decades to unravel its carcinogenesis and relationship with conventional urothelial carcinoma, the exact classification of inverted urothelial lesions is a matter of debate. The morphological features of UC-IGP pose several issues in differential diagnosis with other mostly benign lesions. Various techniques, including immunohistochemistry, UroVysion, and many molecular methods, have been employed to study the exact nature of this lesion. The aim of this review is to provide a comprehensive overview of the morphological and immunophenotypical aspects of UC-IGP. Moreover, we present and discuss the immunohistochemical and molecular markers involved in diagnosis and prognosis of UC-IGP lesions.

Indexed as

ImmunohistochemistryInverted growth patternMolecular markersUrothelial carcinoma

Identifiers

PMID34111910
PMCPMC8353137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.