Evidence map›Paper›PMID 34111682›Full record

ArticleJournal of critical care2021

Successful treatment of acute spleno-porto-mesenteric vein thrombosis after ChAdOx1 nCoV-19 vaccine. A case report.

Michele Umbrello, Nicola Brena, Ruggero Vercelli, Riccardo Alessandro Foa, Marco Femia, Umberto Rossi, Gian Marco Podda, Francesca Cortellaro, Stefano Muttini

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of critical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Thrombosis with Thrombocytopenia Syndrome After Administration of AZD1222 or Ad26.COV2.S Vaccine for COVID-19: A Systematic Review.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  6. Review
  7. Article
  8. Article
  9. Acute limb ischemia secondary to vaccine-induced thrombotic thrombocytopenia.Annals of vascular surgery. Brief reports and innovations · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Michele UmbrelloSC Anestesia e Rianimazione II, Ospedale San Carlo Borromeo, ASST Santi Paolo e Carlo - Polo Universitario, Milano, Italy. Electronic address: michele.umbrello@asst-santipaolocarlo.it.
Nicola BrenaSC Pronto Soccorso e Degenza Breve, Ospedale San Carlo Borromeo, ASST Santi Paolo e Carlo - Polo Universitario, Milano, Italy.
Ruggero VercelliSC Radiologia I, Ospedale San Carlo Borromeo, ASST Santi Paolo e Carlo - Polo Universitario, Milano, Italy.
Riccardo Alessandro FoaSC Radiologia I, Ospedale San Carlo Borromeo, ASST Santi Paolo e Carlo - Polo Universitario, Milano, Italy.
Marco FemiaSC Radiologia I, Ospedale San Carlo Borromeo, ASST Santi Paolo e Carlo - Polo Universitario, Milano, Italy.
Umberto RossiSSD UO a Direzione Universitaria di Radiologia Vascolare ed Interventistica, Ospedale Galliera, Genova, Italy.
Gian Marco PoddaSC Medicina Generale II, Ospedale Paolo, ASST Santi Paolo e Carlo - Polo Universitario, Milano, Italy.
Francesca CortellaroSC Pronto Soccorso e Degenza Breve, Ospedale San Carlo Borromeo, ASST Santi Paolo e Carlo - Polo Universitario, Milano, Italy.
Stefano MuttiniSC Anestesia e Rianimazione II, Ospedale San Carlo Borromeo, ASST Santi Paolo e Carlo - Polo Universitario, Milano, Italy.
Azienda Socio Sanitaria Territoriale Santi Paolo e CarloOspedale San Carlo · ITEnte Ospedaliero Ospedali Galliera · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several cases of deep venous thrombosis in people who had recently received Vaxzevria (previously known as COVID-19 Vaccine AstraZeneca) have recently been reported, mainly presenting as cerebral vein/cerebral venous sinus thrombosis. This syndrome has been termed "vaccine-induced immune thrombotic thrombocytopenia (VITT)". Acute spleno-porto-mesenteric vein thrombosis is an uncommon but serious condition with potential sequelae, such as small-bowel gangrene and end-stage liver failure. We describe a case of concomitant thrombosis of portal, superior mesenteric and splenic veins in a young female patient with no other risk factors who received Vaxzevria (previously ChAdOx1 nCoV-19 vaccine, AstraZeneca) 17 days before. The diagnostic workup and the successful endovascular treatment and systemic anticoagulation management is reported.

Indexed as

COVID-19ThrombosisVaccinesChAdOx1 nCoV-19COVID-19 VaccinesFemaleHumansMesenteric VeinsSARS-CoV-2ChAdOx1 nCoV-19COVID-19 VaccinesVaccinesCOVID-19 vaccineSplanchnic thrombosisThrombocytopeniaUltrasound-enhanced thrombolysisVITT

Identifiers

PMID34111682
PMCPMC9735233
OpenAlexW3170910087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.