Evidence map›Paper›PMID 34111679›Full record

ReviewCurrent opinion in microbiology2021

The microbial and host factors that govern Candida gastrointestinal colonization and dissemination.

Animesh Anand Mishra, Andrew Y Koh

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. microLife · 2026
    Article
  3. Review
  4. Acetate modulates the inhibitory effect ofMicrobial cell (Graz, Austria) · 2023
    Article
  5. iScience · 2023
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Animesh Anand MishraDepartment of Pediatrics, University of Texas, Southwestern Medical Center, Dallas, TX 75390, USA.
Andrew Y KohDepartment of Pediatrics, University of Texas, Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pediatrics, Division of Hematology/Oncology, University of Texas, Southwestern Medical Center, Dallas, TX, USA; Department of Microbiology, University of Texas, Southwestern Medical Center, Dallas, TX, USA; Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: Andrew.koh@utsouthwestern.edu.

Funding

Candida Albicans Gastrointestinal Colonization and DisseminationR01AI123163 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI KOH, ANDREW · 2016 to 2020
$2.0M
Mentoring Patient Oriented Research in the Microbiome of Cancer and Stem Cell Transplant PatientsK24AI150992 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI KOH, ANDREW · 2020 to 2024
$592k
NIAID NIH HHS K24 AI150992NIAID NIH HHS R01 AI123163
6 · The paper itself

Abstract

Candida species are among the most prevalent and abundant members of the gut mycobiota, with Candida albicans (CA) being the most prominent member. CA colonizes numerous mucosal surfaces, most notably the gastrointestinal (GI) and genitourinary tracts. In a healthy host, CA is a pathobiont that exists as a commensal but can become pathogenic if the host's immune system becomes suppressed. The microbial and/or host factors that dictate CA's ability to colonize mucosal surfaces and its ability to disseminate remain of great interest. Here, we review the recent advances and insights regarding Candida colonization and dissemination of the mammalian GI tract.

Indexed as

CandidaGastrointestinal TractAnimalsCandida albicansMucous MembraneSymbiosis

Identifiers

PMID34111679
PMCPMC8822460

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.