Evidence map›Paper›PMID 34111558›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2021

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Jia-Xiang Zhang, Pei-Jie Huang, Da-Peng Wang, Wen-Yu Yang, Jian Lu, Yong Zhu, Xiao-Xiao Meng, Xin Wu, Qiu-Hai Lin, Hui Lv and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. mExperimental and therapeutic medicine · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. mJournal of translational medicine · 2025
    Article
  8. The Emerging Role of METTL3 in Lung Diseases.International journal of molecular sciences · 2025
    Review
  9. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  10. Article
  11. Article
  12. ALKBH3-Mediated MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  13. Article
  14. Review
  15. METTL3-mCell death discovery · 2025
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Jia-Xiang ZhangDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Pei-Jie HuangDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Da-Peng WangDepartment of Intensive Medicine, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214021, China.
Wen-Yu YangDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Jian LuDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Yong ZhuDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Xiao-Xiao MengDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Xin WuDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Qiu-Hai LinDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Hui LvDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China.
Hui XieDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China. Electronic address: xymtm@163.com.
Rui-Lan WangDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, 650 Xinsongjiang Rd, Shanghai 201620, China. Electronic address: wangyusun@hotmail.com.
Shanghai First People's Hospital · CNXinHua Hospital · CNWuxi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic, fatal lung disease characterized by progressive and non-reversible abnormal matrix deposition in lung parenchyma. Myofibroblasts originating mainly from resident fibroblasts via fibroblast-to-myofibroblast transition (FMT) are the dominant collagen-producing cells in pulmonary fibrosis. N

Indexed as

Idiopathic Pulmonary FibrosisMyofibroblastsAnimalsBleomycinEther-A-Go-Go Potassium ChannelsFibroblastsHumansLungMethyltransferasesMiceMice, Inbred C57BLProtein BiosynthesisBleomycinEther-A-Go-Go Potassium ChannelsKCNH6 protein, humanMethyltransferasesMETTL3 protein, humanfibroblast-to-myofibroblast transitionKCNH6m(6)A modificationMETTL3pulmonary fibrosisYTHDF1

Identifiers

PMID34111558
PMCPMC8636177
OpenAlexW3172002214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.