Evidence map›Paper›PMID 34111527›Full record

ReviewBiochimica et biophysica acta. Molecular and cell biology of lipids2021

Courier service for phosphatidylinositol: PITPs deliver on demand.

Tim G Ashlin, Nicholas J Blunsom, Shamshad Cockcroft

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta. Molecular and cell biology of lipids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
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  4. Phosphatidylinositol transfer protein α binds microcolins in its open conformation.Acta crystallographica. Section D, Structural biology · 2026
    Article
  5. Article
  6. Article
  7. Golgi Drivers of Cancer.Sub-cellular biochemistry · 2026
    Review
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  13. Review
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tim G AshlinDept. of Neuroscience, Physiology and Pharmacology, Division of Biosciences, University College London, London WC1E 6JJ, UK.
Nicholas J BlunsomDept. of Neuroscience, Physiology and Pharmacology, Division of Biosciences, University College London, London WC1E 6JJ, UK.
Shamshad CockcroftDept. of Neuroscience, Physiology and Pharmacology, Division of Biosciences, University College London, London WC1E 6JJ, UK. Electronic address: s.cockcroft@ucl.ac.uk.
University College London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/J005606/1British Heart Foundation FS/15/73/31672
6 · The paper itself

Abstract

Phosphatidylinositol is the parent lipid for the synthesis of seven phosphorylated inositol lipids and each of them play specific roles in numerous processes including receptor-mediated signalling, actin cytoskeleton dynamics and membrane trafficking. PI synthesis is localised to the endoplasmic reticulum (ER) whilst its phosphorylated derivatives are found in other organelles where the lipid kinases also reside. Phosphorylation of PI to phosphatidylinositol (4,5) bisphosphate (PI(4,5)P

Indexed as

Endoplasmic ReticulumPhosphatidylinositolsPhospholipid Transfer ProteinsAnimalsCell MembraneGolgi ApparatusHumansPhosphatidylinositol PhosphatesPhosphorylationSignal TransductionType C Phospholipasesphosphatidylinositol 4-phosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsPhospholipid Transfer ProteinsType C PhospholipasesGolgiLipid transferMembrane trafficPhosphatidic acidPhosphatidylinositolPhospholipase CPITPNC1

Identifiers

PMID34111527
PMCPMC8266687
OpenAlexW3171565264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.