Evidence map›Paper›PMID 34111337›Full record

ArticleBiomedica : revista del Instituto Nacional de Salud2021

Chronic Cystoisospora belli infection in a Colombian patient living with HIV and poor adherence to highly active antiretroviral therapy.

Ana Luz Galván-Díaz, Juan Carlos Alzate, Esteban Villegas, Sofía Giraldo, Jorge Botero, Gisela García-Montoya

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Biomedica : revista del Instituto Nacional de Salud, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ana Luz Galván-DíazGrupo de Microbiología Ambiental, Escuela de Microbiología, Universidad de Antioquia, Medellín, Colombia. ana.galvan@udea.edu.co.
Juan Carlos AlzateUnidad de Micología Médica y Experimental, Corporación para Investigaciones Biológicas-Universidad de Santander, Medellín, Colombia; Unidad de Investigación Clínica, Corporación para Investigaciones Biológicas, Medellín, ColombiaUnidad de Micología Médica y Experimental, Corporación para Investigaciones Biológicas-Universidad de Santander, Medellín, Colombia; Unidad de Investigación Clínica, Corporación para Investigaciones Biológicas, Medellín, Colombia. jalzate@cib.org.co.
Esteban VillegasUnidad de Investigación Clínica, Corporación para Investigaciones Biológicas, Medellín, Colombia. estebanvia92@hotmail.com.
Sofía GiraldoUnidad de Investigación Clínica, Corporación para Investigaciones Biológicas, Medellín, Colombia. sofigiraldo92@hotmail.com.
Jorge BoteroUnidad de Micología Médica y Experimental, Corporación para Investigaciones Biológicas-Universidad de Santander, Medellín, Colombia; Grupo de Parasitología, Facultad de Medicina; Corporación Académica para el Estudio de las Patologías Tropicales, Universidad de Antioquia, Medellín, Colombia. jorge.botero@udea.edu.co.
Gisela García-MontoyaCentro Nacional de Secuenciación Genómica, Sede de Investigación Universitaria, Universidad de Antioquia, Medellín, Colombia. gisela.garcia@udea.edu.co.
Corporación para Investigaciones Biológicas · COUniversidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystoisospora belli is an intestinal Apicomplexan parasite associated with diarrheal illness and disseminated infections in humans, mainly immunocompromised individuals such as those living with the human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS). An irregular administration of highly active antiretroviral therapy (HAART) in HIV patients may increase the risk of opportunistic infections like cystoisosporiasis. We describe here a case of C. belli infection in a Colombian HIV patient with chronic gastrointestinal syndrome and poor adherence to HAART. His clinical and parasitological cure was achieved with trimethoprim-sulfamethoxazole treatment. Although a reduction in the number of C. belli cases has been observed since the use of HAART, this parasite still has to be considered as a differential diagnosis of diarrheal disease in HIV/AIDS patients. Effective interventions enhancing adherence to HAART should be included in HIV patient care programs.

Indexed as

Acquired Immunodeficiency SyndromeAntiretroviral Therapy, Highly ActiveHIV InfectionsIsosporiasisColombiaDiarrheaHumansacquired immunodeficiency syndromeantiretroviral therapyApicomplexaColombiadiarrheahighly activeHIV

Identifiers

PMID34111337
PMCPMC8318389
OpenAlexW3164471095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.