Evidence map›Paper›PMID 34111215›Full record

Observational studyPloS one2021

Continuous glucose monitoring in obese pregnant women with no hyperglycemia on glucose tolerance test.

Rosa Maria Rahmi, Priscila de Oliveira, Luciano Selistre, Paulo Cury Rezende, Gabriela Neuvald Pezzella, Pâmela Antoniazzi Dos Santos, Daiane de Oliveira Pereira Vergani, Sônia Regina Cabral Madi, José Mauro Madi

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rosa Maria RahmiDepartment of Endocrinology, General Hospital of Caxias do Sul, Caxias do Sul University, Caxias do Sul, RS, Brazil.
Priscila de OliveiraMaster Degree Student in Health Sciences, Caxias do Sul University, Caxias do Sul, RS, Brazil.
Luciano SelistreDepartment of Nephrology, General Hospital of Caxias do Sul, Caxias do Sul, RS, Brazil.
Paulo Cury RezendeDepartment of Atherosclerosis, Heart Institute of the University of São Paulo Medical School, São Paulo, SP, Brazil.
Gabriela Neuvald PezzellaInstitutional Scientific Initiation Scholarship Program of Caxias do Sul University, Caxias do Sul, RS, Brazil.
Pâmela Antoniazzi Dos SantosDepartment of Nutrition, Caxias do Sul University, Caxias do Sul, RS, Brazil.
Daiane de Oliveira Pereira VerganiDepartment of Nursing, Caxias do Sul University, Caxias do Sul, RS, Brazil.ORCID 0000-0003-2510-1740
Sônia Regina Cabral MadiDepartment of Obstetrics and Gynecology, General Hospital of Caxias do Sul, Caxias do Sul University, Caxias do Sul, RS, Brazil.
José Mauro MadiDepartment of Obstetrics and Gynecology, General Hospital of Caxias do Sul, Caxias do Sul University, Caxias do Sul, RS, Brazil.
Universidade de Caxias do Sul · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of the present study was to compare 24-hour glycemic levels between obese pregnant women with normal glucose tolerance and non-obese pregnant women.

methodsIn the present observational, longitudinal study, continuous glucose monitoring was performed in obese pregnant women with normal oral glucose tolerance test with 75 g of glucose between the 24th and the 28th gestational weeks. The control group (CG) consisted of pregnant women with normal weight who were selected by matching the maternal age and parity with the same characteristics of the obese group (OG). Glucose measurements were obtained during 72 hours.

resultsBoth the groups were balanced in terms of baseline characteristics (age: 33.5 [28.7-36.0] vs. 32.0 [26.0-34.5] years, p = 0.5 and length of pregnancy: 25.0 [24.0-25.0] vs. 25.5 [24.0-28.0] weeks, p = 0.6 in the CG and in the OG, respectively). Pre-breakfast glycemic levels were 77.77 ± 10.55 mg/dL in the CG and 82.02 ± 11.06 mg/dL in the OG (p<0.01). Glycemic levels at 2 hours after breakfast were 87.31 ± 13.10 mg/dL in the CG and 93.48 ± 18.74 mg/dL in the OG (p<0.001). Daytime blood glucose levels were 87.6 ± 15.4 vs. 93.1 ± 18.3 mg/dL (p<0.001) and nighttime blood glucose levels were 79.3 ± 15.8 vs. 84.7 ± 16.3 mg/dL (p<0.001) in the CG and in the OG, respectively. The 24-hour, daytime, and nighttime values of the area under the curve were higher in the OG when compared with the CG (85.1 ± 0.16 vs. 87.9 ± 0.12, 65.6 ± 0.14 vs. 67.5 ± 0.10, 19.5 ± 0.07 vs. 20.4 ± 0.05, respectively; p<0.001).

conclusionThe results of the present study showed that obesity in pregnancy was associated with higher glycemic levels even in the presence of normal findings on glucose tolerance test.

Indexed as

AdultArea Under CurveBlood Glucose Self-MonitoringCase-Control StudiesFemaleGlucose Tolerance TestHumansLongitudinal StudiesObesityPregnancyPregnancy Trimester, SecondPregnant PeopleProspective Studies

Identifiers

PMID34111215
PMCPMC8191902
OpenAlexW3171398065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.