Evidence map›Paper›PMID 34110966›Full record

ArticlePharmaceutical biology2021

Extract of

Weiming Lin, Li Gu, Ling-Yan Zhu, Sha Zhou, Danhong Lian, Yongquan Xu, Limin Zheng, Xin Liu, Lian Li

Abstract read
In one paragraph

Article in Pharmaceutical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. CanPharmaceuticals (Basel, Switzerland) · 2025
    Review
  3. International journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Weiming LinMOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Li GuAcademy of Food and Health Engineering, Sun Yat-Sen University, Guangzhou, China.
Ling-Yan ZhuMOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Sha ZhouAcademy of Food and Health Engineering, Sun Yat-Sen University, Guangzhou, China.
Danhong LianAcademy of Food and Health Engineering, Sun Yat-Sen University, Guangzhou, China.
Yongquan XuMOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Limin ZhengMOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Xin LiuAcademy of Food and Health Engineering, Sun Yat-Sen University, Guangzhou, China.
Lian LiMOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0001-8803-0930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

context

objectiveWe investigated the antitumor activity and mechanism of an extract from MATERIALS AND

methodsA

resultsGSE suppressed the proliferation of HepG2 cells (IC DISCUSSION AND

conclusionsOur findings provide new evidence that GSE suppresses growth of cancer cells

Indexed as

Antineoplastic AgentsCarcinoma, HepatocellularCell Cycle CheckpointsCell ProliferationCinnamatesDose-Response Relationship, DrugEndoplasmic Reticulum StressGanodermaHep G2 CellsHumansInhibitory Concentration 50Liver NeoplasmsSpores, FungalThioureaUp-RegulationAntineoplastic AgentsCinnamatessalubrinalThioureaAntitumor activityhepatocellular carcinomaunfolded protein response

Identifiers

PMID34110966
PMCPMC8205061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.