Evidence map›Paper›PMID 34110911›Full record

ReviewCirculation research2021

Leveraging Machine Learning and Artificial Intelligence to Improve Peripheral Artery Disease Detection, Treatment, and Outcomes.

Alyssa M Flores, Falen Demsas, Nicholas J Leeper, Elsie Gyang Ross

Open access · bronzeAbstract readReview
In one paragraph

Review in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 120 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alyssa M FloresDepartment of Surgery, Division of Vascular Surgery (A.M.F., F.D., N.J.L., E.G.R.), Stanford University School of Medicine, CA.
Falen DemsasDepartment of Surgery, Division of Vascular Surgery (A.M.F., F.D., N.J.L., E.G.R.), Stanford University School of Medicine, CA.
Nicholas J LeeperDepartment of Surgery, Division of Vascular Surgery (A.M.F., F.D., N.J.L., E.G.R.), Stanford University School of Medicine, CA.
Elsie Gyang RossDepartment of Surgery, Division of Vascular Surgery (A.M.F., F.D., N.J.L., E.G.R.), Stanford University School of Medicine, CA.
Cardiovascular Institute of the South · USStanford University · US

Funding

Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
Clonal expansion, resistance to efferocytosis and innate immunity in atherosclerosisR35HL144475 · NHLBI · STANFORD UNIVERSITY · PI LEEPER, NICHOLAS JAMES · 2019 to 2024
$5.1M
UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
Using Artificial Intelligence to Enable Early Identification and Treatment of Peripheral Artery DiseaseK01HL148639 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ROSS, ELSIE GYANG · 2019 to 2023
$807k
Replacement of Small Animal Echocardiographic InstrumentationS10OD010417 · OD · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI ROSS, ROBERT SCOTT · 2012 to 2012
$371k
NHLBI NIH HHS K01 HL148639NHLBI NIH HHS R25 HL145817NHLBI NIH HHS R35 HL144475NHLBI NIH HHS T32 HL007444NIH HHS S10 OD010417
6 · The paper itself

Abstract

Peripheral artery disease is an atherosclerotic disorder which, when present, portends poor patient outcomes. Low diagnosis rates perpetuate poor management, leading to limb loss and excess rates of cardiovascular morbidity and death. Machine learning algorithms and artificially intelligent systems have shown great promise in application to many areas in health care, such as accurately detecting disease, predicting patient outcomes, and automating image interpretation. Although the application of these technologies to peripheral artery disease are in their infancy, their promises are tremendous. In this review, we provide an introduction to important concepts in the fields of machine learning and artificial intelligence, detail the current state of how these technologies have been applied to peripheral artery disease, and discuss potential areas for future care enhancement with advanced analytics.

Indexed as

Artificial IntelligenceAlgorithmsAortic AneurysmAtherosclerosisBehavior TherapyCarotid Artery DiseasesForecastingHumansImage Interpretation, Computer-AssistedLife StyleMachine LearningNatural Language ProcessingPeripheral Arterial DiseasePhenotypePrognosisRisk Assessmentartificial intelligencedeep learningmachine learningperipheral artery diseaseprecision medicinevascular disease

Identifiers

PMID34110911
PMCPMC8285054
OpenAlexW3170220376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.