Evidence map›Paper›PMID 34110616›Full record

SynthesisEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2022

Can molar incisor hypomineralization cause dental fear and anxiety or influence the oral health-related quality of life in children and adolescents?-a systematic review.

B Jälevik, N Sabel, A Robertson

2 registry-linked trialsOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 4 pooled it
7.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07389148 recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of Salivary Cortisol Levels and Physiological Stress Parameters in Children With Molar Incisor Hypomineralization: A Comparative Observational Study

TypeobservationalSponsorLokman Hekim UniversityRan2026 to 2026Enrolled90ConditionsMolar Incisor Hypomineralization
NCT07457450 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Evaluating the Effectiveness of Intraosseous Anesthesia During Restorative Procedures on Teeth Affected by Molar Incisive Hypomineralization in Children

TypeinterventionalSponsorUniversity of ZagrebRan2023 to 2026Enrolled50ConditionsMolar Incisor HypomineralisationArmsIntraosseous anesthesia., Local infiltration anesthesia
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Effectiveness of different anaesthetic techniques, agents and adjunctive interventions in handling pain during dental treatment of MIH-affected teeth: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
  3. Non- and minimally invasive management of hypersensitivity in molar-incisor hypomineralisation (MIH) at home and in clinical practice: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
  4. Desensitization treatment in MIH-affected teeth: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. Assessment of the effectiveness of intraosseous anaesthesia during restorative procedures on teeth affected by molar incisor hypomineralisation in children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  10. High prevalence of molar-incisor hypomineralisation in sickle cell disease children and the association with haematologic profile: a retrospective cohort study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. To Bleach or Not to Bleach?-The Role of Bleaching in the Clinical Workflow for the Treatment of Demarcated Opacities in Anterior Teeth.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Article
  15. Article
  16. Review
  17. Review
  18. Parental knowledge and perception of Molar Incisor Hypomineralisation (MIH).European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  19. Prevalence of molar incisor hypomineralisation and associated factors amongst 8-year-olds in Ireland.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

B JälevikDepartment of Pediatric Dentistry, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. birgitta.jalevik@gu.se.ORCID http://orcid.org/0000-0002-7634-9423
N SabelDepartment of Pediatric Dentistry, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
A RobertsonDepartment of Pediatric Dentistry, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
University of Gothenburg · SEPublic Dental Service Västra Götaland · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMolar Incisor Hypomineralization (MIH) are first molars with developmental enamel defects and are common findings in many child populations. The porous nature of MIH enamel and the presence of post-eruptive enamel breakdown leads to the presence of hypersensitivity and pain, which is often the patient's main complaint and can result in dental fear and affect the quality of life. The present review aims to summarise the evidence for the ability of MIH to cause problems, such as dental fear and anxiety (DFA) and to summarise the evidence for a possibly negative impact on the oral health-related quality of life (OHRQoL) of MIH affected children and adolescents, in a systematic review.

methodTwo searches, (1) MIH AND dental anxiety and (2) MIH AND Quality of life, were performed in MEDLINE/PubMed and Scopus. Selection demands were fulfilling the MIH diagnosis criteria using validated instruments and questionnaires for assessing DFA and OHRQoL, respectively.

resultsAfter removing duplicates and articles not fulfilling the selection demands, 6 studies concerning MIH and DFA and 8 studies concerning MIH and OHRQoL remained.

conclusionChildren and adolescents with diagnosed MIH did not seem to suffer from increased dental fear and anxiety, but indicated an impaired oral health-related quality of life.

Indexed as

Dental Enamel HypoplasiaQuality of LifeAdolescentChildDental AnxietyHumansIncisorPrevalenceDental fear and anxietyMolar incisor hypomineralization (MIH)Review

Identifiers

PMID34110616
PMCPMC8927003
OpenAlexW3167870557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.