SynthesisEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2022
An update of treatment modalities in children and adolescents with teeth affected by molar incisor hypomineralisation (MIH): a systematic review.
Synthesis in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 77 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Performance of Giomer Preceded by Etching Versus Resin-Based Sealants Applied on Permanent Molars Affected by Molar-Incisor Hypo-mineralization: A Randomized Clinical Trial
Clinical Evaluation of Graphene-Reinforced CAD/CAM Indirect Restorations in Molars Affected by Molar-Incisor Hypomineralization (MIH) in Adolescents: A Clinical Study
Who cites it
77 citing papers in PubMed, 8 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Effectiveness of different anaesthetic techniques, agents and adjunctive interventions in handling pain during dental treatment of MIH-affected teeth: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Non- and minimally invasive management of hypersensitivity in molar-incisor hypomineralisation (MIH) at home and in clinical practice: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Restorative interventions and management of primary and permanent molars affected by molar incisor hypo-mineralization: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Diode and er: YAG laser therapy versus other desensitizing treatments for dentin hypersensitivity in molar-incisor hypomineralization: a systematic review.Lasers in medical science · 2026Pooled it
- Association of hypomineralized second primary molars (HSPM) and hypomineralized primary canines (HPC) with molar-incisor hypomineralization (MIH): a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Desensitization treatment in MIH-affected teeth: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Pooled it
- Pretreatments to bonding on enamel and dentin disorders: a systematic review.Evidence-based dentistry · 2024Pooled it
- Is there a rise of prevalence for Molar Incisor Hypomineralization? A meta-analysis of published data.BMC oral health · 2024Pooled it
- Clinical performance of glass hybrid and short fiber-reinforced composite restorations in MIH-affected molars: A 60-month split-mouth randomized controlled trial.Clinical oral investigations · 2026Trial
- Zirconia-reinforced glass ionomer restorations in molar incisor hypomineralization: a randomized controlled clinical trial.Clinical oral investigations · 2025Trial
- Outcome of vital pulp therapy in deeply carious molars affected with molar incisor hypomineralisation (MIH) defects: a randomized clinical trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2022Trial
- Effects of different remineralization agents on MIH defects: a randomized clinical study.Clinical oral investigations · 2022Trial
- Esthetic Rehabilitation of Anterior Teeth With Diastemas and MIH-Related Enamel Opacities.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Article
- Oral Health-Related Quality of Life in Pediatric Subjects with Molar Incisor Hypomineralization: An Umbrella Review of Domain-Specific Impact and Treatment-Related Changes.Children (Basel, Switzerland) · 2026Review
- Clinical Challenges in the Management of Complex Tooth Impaction and Transposition: A Case Series.Children (Basel, Switzerland) · 2026Article
- Effect of Deproteinization on the Clinical Success of Composite Restorations in Molars Affected by Molar-Incisor Hypomineralization.Children (Basel, Switzerland) · 2026Article
- Article
- The emerging role of digital dentistry in managing molar-incisor hypomineralization: A perspective.PLOS digital health · 2026Article
- Prevalence, clinical characteristics, and treatment needs of Molar Incisor Hypomineralization (MIH) in Turkish children: a cross-sectional study.BMC public health · 2026Article
- Comparison of different cavity patterns and treatment methods in molars with molar-incisor hypomineralization (MIH) - retrospective 9 months results.BMC oral health · 2026Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo systematically review the treatment modalities for molar-incisor hypomineralisation for children under the age of 18 years. The research question was, 'What are the treatment options for teeth in children affected by molar incisor hypomineralisation?'
methodsAn electronic search of the following electronic databases was completed MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, LILACS, Google Scholar and Open Grey identifying studies from 1980 to 2020. The PRISMA guidelines were followed. The studies were screened, data extracted and calibration was completed by two independent reviewers.
resultsOf 6220 potential articles, 34 studies were included. Twenty studies investigated management of molars with fissure sealants, glass ionomer cement, polyacid modified resin composite, composite resin, amalgam, preformed metal crowns, laboratory-manufactured crowns and extractions. In four articles management of incisors with microabrasion, resin-infiltration and a combination of approaches was reported. Eight studies looked at strategies to mineralise MIH-affected teeth and/or reduce hypersensitivity. Two studies investigated patient-centred outcomes following treatment. Due to the heterogeneity between the studies, meta-analysis was not performed.
conclusionThe use of resin-based fissure sealants, preformed metal crowns, direct composite resin restorations and laboratory-made restorations can be recommended for MIH-affected molars. There is insufficient evidence to support specific approaches for the management of affected incisors. Products containing CPP-ACP may be beneficial for MIH-affected teeth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.