Evidence map›Paper›PMID 34110533›Full record

ReviewInflammopharmacology2021

Role of vitamins and minerals as immunity boosters in COVID-19.

Puneet Kumar, Mandeep Kumar, Onkar Bedi, Manisha Gupta, Sachin Kumar, Gagandeep Jaiswal, Vikrant Rahi, Narhari Gangaram Yedke, Anjali Bijalwan, Shubham Sharma and 1 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Inflammopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 167 citations in OpenAlex.

  1. Pooled it
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  7. Antioxidants (Basel, Switzerland) · 2025
    Review
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Puneet KumarDepartment of Pharmacology, Central University of Punjab, Ghudda-151401, Bathinda, Punjab, India. punnubansal79@gmail.com.ORCID http://orcid.org/0000-0002-7978-1043
Mandeep KumarDepartment of Pharmacology and Toxicology, University of Genoa, Genoa, Italy.
Onkar BediChitkara College of Pharmacy, Chitkara University, Punjab, India.
Manisha GuptaChitkara College of Pharmacy, Chitkara University, Punjab, India.
Sachin KumarDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, India.
Gagandeep JaiswalDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, India.ORCID http://orcid.org/0000-0002-5972-8130
Vikrant RahiDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, India.
Narhari Gangaram YedkeDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, India.
Anjali BijalwanDepartment of Pharmacology, Central University of Punjab, Ghudda-151401, Bathinda, Punjab, India.
Shubham SharmaDepartment of Pharmacology, Central University of Punjab, Ghudda-151401, Bathinda, Punjab, India.
Sumit JamwalDepartment of Psychiatry, Yale School of Medicine, Yale University, New Haven, CT, 06511, USA.
Maharaja Ranjit Singh Punjab Technical University · INCentral University of Punjab · INChitkara University · INUniversity of Genoa · ITYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) known as coronavirus disease (COVID-19), emerged in Wuhan, China, in December 2019. On March 11, 2020, it was declared a global pandemic. As the world grapples with COVID-19 and the paucity of clinically meaningful therapies, attention has been shifted to modalities that may aid in immune system strengthening. Taking into consideration that the COVID-19 infection strongly affects the immune system via multiple inflammatory responses, pharmaceutical companies are working to develop targeted drugs and vaccines against SARS-CoV-2 COVID-19. A balanced nutritional diet may play an essential role in maintaining general wellbeing by controlling chronic infectious diseases. A balanced diet including vitamin A, B, C, D, E, and K, and some micronutrients such as zinc, sodium, potassium, calcium, chloride, and phosphorus may be beneficial in various infectious diseases. This study aimed to discuss and present recent data regarding the role of vitamins and minerals in the treatment of COVID-19. A deficiency of these vitamins and minerals in the plasma concentration may lead to a reduction in the good performance of the immune system, which is one of the constituents that lead to a poor immune state. This is a narrative review concerning the features of the COVID-19 and data related to the usage of vitamins and minerals as preventive measures to decrease the morbidity and mortality rate in patients with COVID-19.

Indexed as

Dietary SupplementsCOVID-19HumansImmune SystemMicronutrientsMineralsVitaminsMicronutrientsMineralsVitaminsCorona virusCOVID-19MineralsTherapyVitamin

Identifiers

PMID34110533
PMCPMC8190991
OpenAlexW3170746437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.