Evidence map›Paper›PMID 34110522›Full record

ReviewCurrent treatment options in oncology2021

Cardiovascular Complications Associated with Contemporary Lung Cancer Treatments.

Kazuhiro Sase, Yasuhito Fujisaka, Masaaki Shoji, Mikio Mukai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current treatment options in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Radiation Treatment Mechanisms of Cardiotoxicity: A Systematic Review.International journal of molecular sciences · 2023
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Lung cancer and risk of cardiovascular mortality.Frontiers in cardiovascular medicine · 2024
    Article
  7. Cardiovascular disease in thymic cancer patients.Frontiers in cardiovascular medicine · 2024
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kazuhiro SaseClinical Pharmacology and Regulatory Science, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. sase@juntendo.ac.jp.ORCID 0000-0002-2714-304X
Yasuhito FujisakaDepartment of Respiratory Medicine and Thoracic Oncology/Clinical Research Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.
Masaaki ShojiDepartment of General Internal Medicine/Oncologic Emergencies, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Mikio MukaiOsaka Prefectural Hospital Organization, Osaka International Cancer Institute, Department of Medical Check-up, Osaka, Japan.
Osaka International Cancer Institute · JPWaseda University · JP

Funding

Japan Agency for Medical Research and Development 20ck0106633h0001Japan Society for the Promotion of Science 18K12134Japan Society for the Promotion of Science 20K08427Ministry of Health, Labour and Welfare 20KC2009Ministry of Health, Labour and Welfare (JP) 20FA1801
6 · The paper itself

Abstract

opinion statementLung cancer is the most common form of cancer in humans and the leading cause of cancer-related death worldwide. Traditionally, lung cancer has been diagnosed as either small cell lung cancer (SCLC) or non-small cell lung cancer (NSCLC). However, recent developments in molecular pathology have revolutionized the diagnosis and treatment of the disease, thus improving patient prognosis and increasing the number of survivors. In advanced NSCLC cases, molecularly targeted drugs for patients with positive driver gene mutation/rearrangement, and immune checkpoint inhibitors for those with a positive biomarker, have changed the standard of care. SCLC is a highly malignant entity. In addition to the chemotherapy and radiotherapy, immune checkpoint inhibitors have recently provided some hope for extended-stage SCLC. Smoking cessation is related to decreased morbidity. However, early metastasis remains a significant challenge. Recently, cancer therapy-related cardiovascular disease (CTRCD) has emerged as diverse pathophysiology, including fulminant myocarditis, fatal arrhythmia, pericarditis, hypertension, and thrombosis, that emerged with modern lung cancer therapies. Cardio-oncology is a new interdisciplinary collaboration to develop methodologies to manage cardiovascular risk factors and CTRCDs with the common goal of minimizing unnecessary interruption of cancer treatment and maximizing outcomes of lung cancer survivors.

Indexed as

Anaplastic Lymphoma KinaseAntineoplastic AgentsCardiovascular DiseasesErbB ReceptorsHumansLung NeoplasmsMolecular Targeted TherapyProto-Oncogene Proteins B-rafAnaplastic Lymphoma KinaseAntineoplastic AgentsErbB ReceptorsProto-Oncogene Proteins B-rafCancer therapy–related cardiovascular disease (CTRCD)Cardio-oncologyCardiotoxicityLung cancer

Identifiers

PMID34110522
OpenAlexW3167253307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.