Evidence map›Paper›PMID 34110458›Full record

ArticleWorld journal of surgery2021

Potentially Avertable Child Mortality Associated with Surgical Workforce Scale-up in Low- and Middle-Income Countries: A Global Study.

Paul Truche, Fabio Botelho, Alexis N Bowder, Alexander W Levis, Sarah L M Greenberg, Emily Smith, Scott Corlew, Stephen Bickler, Henry E Rice, Emmanuel A Ameh and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Care pathways for pediatric surgical conditions.World journal of pediatric surgery · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 4 countries.

Paul TrucheProgram in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA. paul.truche@gmail.com.ORCID http://orcid.org/0000-0001-6511-9887
Fabio BotelhoDivision of Pediatric Surgery, Hospital das Clínicas, UFMG, Belo Horizonte, Minas Gerais, Brazil.
Alexis N BowderProgram in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.
Alexander W LevisDepartment of Biostatistics, Harvard School of Public Health, Boston, MA, USA.
Sarah L M GreenbergDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA, USA.
Emily SmithDuke Global Health Institute, Durham, NC, USA.
Scott CorlewProgram in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.
Stephen BicklerRady Children's Hospital, University of California, San Diego, San Diego, CA, USA.
Henry E RiceDuke Global Health Institute, Durham, NC, USA.
Emmanuel A AmehDepartment of Pediatric Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
John G MearaProgram in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.
Dan PoenaruDepartment of Pediatric Surgery, McGill University Health Centre, Montreal, QC, USA.
David P MooneyDepartment of Pediatric Surgery, Boston Children's Hospital, Boston, MA, USA.
Global Initiative for Children’s Surgery
Harvard University · USBoston Children's Hospital · USDuke Institute for Health Innovation · USAhmadu Bello University Teaching Hospital · NGHospital das Clínicas da Universidade Federal de Minas Gerais · BRMcGill University Health Centre · CASeattle Children's Hospital · USUniversity of California San Diego · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
NCATS NIH HHS UL1 TR002541
6 · The paper itself

Abstract

backgroundExpansion of access to surgical care can improve health outcomes, although the impact that scale-up of the surgical workforce will have on child mortality is poorly defined. In this study, we estimate the number of child deaths potentially avertable by increasing the surgical workforce globally to meet targets proposed by the Lancet Commission on Global Surgery.

methodsTo estimate the number of deaths potentially avertable through increases in the surgical workforce, we used log-linear regression to model the association between surgeon, anesthetist and obstetrician workforce (SAO) density and surgically amenable under-5 mortality rate (U5MR), infant mortality rate (IMR), and neonatal mortality rate (NMR) for 192 countries adjusting for potential confounders of childhood mortality, including the non-surgical workforce (physicians, nurses/midwives, community health workers), gross national income per capita, poverty rate, female literacy rate, health expenditure per capita, percentage of urban population, number of surgical operations, and hospital bed density. Surgically amenable mortality was determined using mortality estimates from the UN Inter-agency Group for Child Mortality Estimation adjusted by the proportion of deaths in each country due to communicable causes unlikely to be amenable to surgical care. Estimates of mortality reduction due to upscaling surgical care to support the Lancet Commission on Global Surgery (LCoGS) minimum target of 20-40 SAO/100,000 were calculated accounting for potential increases in surgical volume associated with surgical workforce expansion.

resultsIncreasing SAO workforce density was independently associated with lower surgically amenable U5MR as well as NMR (p < 0.01 for each model). When accounting for concomitant increases in surgical volume, scale-up of the surgical workforce to 20-40 SAO/100,000 could potentially prevent between 262,709 (95% CI 229,643-295,434) and 519,629 (465,046-573,919) under 5 deaths annually. The majority (61%) of deaths averted would be neonatal deaths.

conclusionScale up of surgical workforce may substantially decrease childhood mortality rates around the world. Our analysis suggests that scale-up of surgical delivery through increase in the SAO workforce could prevent over 500,000 children from dying before the age of 5 annually. This would represent significant progress toward meeting global child mortality reduction targets.

Indexed as

Child MortalityDeveloping CountriesChildFemaleGlobal HealthHumansInfantInfant MortalityInfant, NewbornWorkforce

Identifiers

PMID34110458
OpenAlexW3168747817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.