ArticleDiabetologia2021
Markers of metabolic health and gut microbiome diversity: findings from two population-based cohort studies.
Article in Diabetologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Diet and Exercise Interventions in Pediatric Cancer Survivors and Effects on Cardiometabolic Disease Risk and Inflammaging Biomarkers: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2026Pooled it
- Microbial metabolite-driven mechanisms linking the gut microbiome to atherosclerosis: multi-omic and translational perspectives.Gut microbes · 2026Review
- Associations of Diabetes Mellitus Status and Geriatric Nutritional Risk Index with the Gut Microbiota in Nursing-Home Residents.Nutrients · 2026Article
- Translational Geroscience Strategies for Delaying Multimorbidity.ACS pharmacology & translational science · 2026Review
- Culturally acceptable fermented grain may improve gut health in South African postpartum mothers in a randomised trial.The British journal of nutrition · 2026Article
- Effect of Alpha-Lipoic Acid, Betaine, and L-Carnitine Supplementation on Gut Microbiota and Obesity Biomarkers in Mice.Nutrients · 2026Article
- An altered gut microbiota is associated with anthropometric and biochemical changes in a prediabetes Mexican cohort.Bioscience of microbiota, food and health · 2026Article
- Comparing Mediterranean and Western Diets: Cognitive and Microbiota Effects in Middle-Aged Rats.Current developments in nutrition · 2025Article
- A Comprehensive Pilot Study to Elucidate the Distinct Gut Microbial Composition and Its Functional Significance in Cardio-Metabolic Disease.Biochemical genetics · 2025Article
- Gut dysbiosis patterns in CVID patients with noninfectious complications observed in a germ-free mouse model through fecal microbiota transplantation.Journal of human immunity · 2025Article
- ISCAZIM: Integrated statistical correlation analysis for zero-inflated microbiome data.Heliyon · 2025Article
- Healthy microbiome-moving towards functional interpretation.GigaScience · 2025Article
- Postoperative insulin resistance and the intestinal microbiota: mechanisms and research advances.Microbiome research reports · 2025Review
- Association between the dietary index for gut microbiota and metabolic syndrome: the mediating role of the dietary inflammatory index.Frontiers in nutrition · 2025Article
- Impact of Gut Microbiota and SCFAs in the Pathogenesis of PCOS and the Effect of Metformin Therapy.International journal of molecular sciences · 2024Article
- Associations between gut microbiota and incident fractures in the FINRISK cohort.NPJ biofilms and microbiomes · 2024Article
- Interactions between host and gut microbiota in gestational diabetes mellitus and their impacts on offspring.BMC microbiology · 2024Review
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- High-fat diet feeding exacerbates HIV-1 rectal transmission.mSystems · 2024Article
- Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 5 countries.
Funding
Abstract
aims/hypothesisThe gut microbiome is hypothesised to be related to insulin resistance and other metabolic variables. However, data from population-based studies are limited. We investigated associations between serologic measures of metabolic health and the gut microbiome in the Northern Finland Birth Cohort 1966 (NFBC1966) and the TwinsUK cohort.
methodsAmong 506 individuals from the NFBC1966 with available faecal microbiome (16S rRNA gene sequence) data, we estimated associations between gut microbiome diversity metrics and serologic levels of HOMA for insulin resistance (HOMA-IR), HbA
resultsIn NFBC1966, alpha diversity was lower in individuals with higher HOMA-IR with a mean of 74.4 (95% CI 70.7, 78.3) amplicon sequence variants (ASVs) for the first quartile of HOMA-IR and 66.6 (95% CI 62.9, 70.4) for the fourth quartile of HOMA-IR. Alpha diversity was also lower with higher HbA CONCLUSIONS/
interpretationOverall, higher levels of HOMA-IR, CRP and HbA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.