Evidence map›Paper›PMID 34109866›Full record

SynthesisPerfusion2022

Minimally invasive versus transcatheter closure of secundum atrial septal defects: a systematic review and meta-analysis.

Esther Goh, Haya Mohammed, Mohammad Yusuf Salmasi, Samantha Ho, Umberto Benedetto, Massimo Caputo, Gianni Angelini, Hunaid A Vohra

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Perfusion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Baseline heart rateFrontiers in pediatrics · 2026
    Article
  2. Surgical Treatment of Atrial Septal Defects.Reviews in cardiovascular medicine · 2024
    Review
  3. Minimal-Access Atrial Septal Defect (ASD) Closure.Journal of cardiovascular development and disease · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Esther GohDepartment of Cardiovascular Sciences Surgery, Bristol Hearth Institute, Bristol, UK.
Haya MohammedDepartment of Cardiovascular Sciences Surgery, Bristol Hearth Institute, Bristol, UK.ORCID 0000-0002-6246-4578
Mohammad Yusuf SalmasiSurgery and Cancer, Imperial College London, London, UK.
Samantha HoDepartment of Cardiovascular Sciences Surgery, Bristol Hearth Institute, Bristol, UK.
Umberto BenedettoDepartment of Cardiovascular Sciences Surgery, Bristol Hearth Institute, Bristol, UK.
Massimo CaputoDepartment of Cardiovascular Sciences Surgery, Bristol Hearth Institute, Bristol, UK.
Gianni AngeliniDepartment of Cardiovascular Sciences Surgery, Bristol Hearth Institute, Bristol, UK.ORCID 0000-0002-1753-3730
Hunaid A VohraDepartment of Cardiovascular Sciences Surgery, Bristol Hearth Institute, Bristol, UK.

Funding

British Heart Foundation CH/17/1/32804British Heart Foundation PG/15/33/31394
6 · The paper itself

Abstract

backgroundLimited data exists demonstrating the efficacy of minimally invasive surgery (MIS) compared to transcatheter (TC) closure of atrial septal defects (ASD). This systematic review and meta-analysis aims to compare post-operative outcomes of MIS versus TC repair in ASD closure.

methodsPubMed, Medline and EMBASE were searched from inception until June 2018 for randomised and observational studies comparing post-operative outcomes for MIS and TC repair. The studies were reviewed for bias using the ROBINS-I Score and pooled in a meta-analysis using STATA (version 15).

resultsSix observational studies, involving 1524 patients assessing three primary and five secondary outcomes were included. Evidence suggests TC repair yielded shorter hospital stay (MD = 3.32, 95% CI 1.04-5.60) and lower rates of transient atrial fibrillation (AF) (RR = 0.48, 95% CI 0.20-1.15). TC repair patients also had fewer pericardial effusions (RR = 0.27, 95% CI 0.05-1.54, I

conclusionsMIS closure for ASD has similar outcomes compared to TC repair. However, the lack of randomised literature related to MIS versus TC repair for ASD closure warrants further evidence in the form of RCTs to further support these findings.

Indexed as

Atrial FibrillationHeart Septal Defects, AtrialStrokeCardiac CatheterizationHumansMinimally Invasive Surgical ProceduresTreatment Outcomeatrial septal defectminimally invasivetranscatheter

Identifiers

PMID34109866
PMCPMC9500175

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.