Evidence map›Paper›PMID 34109538›Full record

SynthesisGeneral thoracic and cardiovascular surgery2021

Can we predict mediastinal lymph nodes metastasis in esophagogastric junction cancer? Results of a systematic review and meta-analysis.

Mohamed Maatouk, Yacine Ben Safta, Ghassen Hamdi Kbir, Aymen Mabrouk, Anis Ben Dhaou, Sami Daldoul, Sofien Sayari, Karim Haouet, Mounir Ben Moussa

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in General thoracic and cardiovascular surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mohamed MaatoukA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia. maatouk.m@yahoo.com.ORCID http://orcid.org/0000-0002-2892-7225
Yacine Ben SaftaA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia.
Ghassen Hamdi KbirA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia.
Aymen MabroukA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia.
Anis Ben DhaouA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia.
Sami DaldoulA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia.
Sofien SayariA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia.
Karim HaouetA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia.
Mounir Ben MoussaA21 Surgery Department, Research Laboratory LR12ES01, Charles Nicolle Hospital, Faculty of Medicine of Tunis/Tunis El Manar University, Rue 9 avril - 1007 Bab Saadoun, Tunis, Tunisia.
Tunis El Manar University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this systematic review and meta-analysis was to define clinical indicator that predicts mediastinal lymph nodes metastasis (MLNM) in patients with Esophagogastric junction cancer (EGJC) to select patient population requiring esophagectomy.

methodsA systematic and electronic search of several electronic databases was performed up to August 2020. Studies containing information on risk factors for MLNM in patients diagnosed with EJGC and who underwent curative surgery were included.

resultsTwo predictors, including undifferentiated type (OR = 1.82, 95% CI = 1.07-3.10, p = 0.03) and esophageal invasion length (EIL) (OR = 10.95, 95% CI = 6.37-18.82, p < 0.00001) were identified as significant predictors for the risk of MLNM.

conclusionKnowledge of the associations of these clinicopathological features with MLNM can be useful in determining operative strategy for EGJC.

Indexed as

AdenocarcinomaEsophageal NeoplasmsStomach NeoplasmsEsophagectomyEsophagogastric JunctionHumansLymphatic MetastasisLymph Node ExcisionLymph NodesRetrospective StudiesAdenocarcinoma of the esophagogastric junctionLymph node metastasisRisk factorThoracotomy

Identifiers

PMID34109538
OpenAlexW3169628106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.