ArticleArchives of dermatological research2022
Optical coherence tomography quantifying photo aging: skin microvasculature depth, epidermal thickness and UV exposure.
Article in Archives of dermatological research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Skin Epidermal and Microvascular Properties at the Sacrum and Heel Assessed with Optical Coherence Tomography.Skin pharmacology and physiology · 2026Article
- Assessing changes in ultraviolet radiation-exposed mouse skin using optical coherence tomography.PloS one · 2025Article
- Different Pathways of Skin Aging: Objective Instrumental Evaluation.Diagnostics (Basel, Switzerland) · 2024Article
- Diameter-dependent classification of dermal vasculature using optical coherence tomography angiography.Quantitative imaging in medicine and surgery · 2024Article
- Pilot study of optical coherence tomography angiography-derived microvascular metrics in hands and feet of healthy and diabetic people.Scientific reports · 2023Article
- Radiation-induced alterations in multi-layered, in-vitro skin models detected by optical coherence tomography and histological methods.PloS one · 2023Article
- The role and safety of UVA and UVB in UV-induced skin erythema.Frontiers in medicine · 2023Article
- Detection of skin thickness and density in healthy Chinese people by using high-frequency ultrasound.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023Article
- Sex Differences in Biological Systems and the Conundrum of Menopause: Potential Commonalities in Post-Menopausal Disease Mechanisms.International journal of molecular sciences · 2022Review
- [Advances in optical coherence tomography].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021Review
- The Effects of Subacute Sunlight Exposure on Skin Thickness: A Pilot Sonographic Study.Journal of medical ultrasoundArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPhoto aging predominantly occurs in the face, neck and hands due to UVA and UVB irradiation. It is associated with skin cancer and histological studies indicate thinning of the epidermis and elastosis occurs. Dynamic Optical coherence tomography (D-OCT) is a non-invasive imaging tool able to visualize the epidermis and upper dermis and its blood vessels as well as to evaluate epidermal thickness (ET) and blood flow.
objectiveTo investigate ET and blood vessel depth using D-OCT in human subjects correlated to UV exposure.
methodsWe evaluated data from 249 healthy adults, that had D-OCT-scans conducted at four different regions (forehead, neck, arm and hand) and correlated ET and blood vessel depth with occupational UV exposure (total standard erythema dose, Total SED), season and demographic data.
resultsRegional differences in ET and blood vessel depth were found (p values < 0.001). Multiple linear regressions showed a seasonal effect on both ET (- 0.113 to - 0.288 µm/day, p values < 0.001) and blood vessel depth (0.168-0.347 µm/day, p values < 0.001-0.007) during August-December. Significant age-related decrease of ET was seen in forehead, arm and hand (0.207-0.328 µm/year, p values = 0.002-0.18) and blood vessel depth in forehead (0.064-0.553 µm/year, p values = 0.01-0.61). Males had thicker epidermis (3.92-10.93 µm, p values = 0.002-0.15).
conclusionChanging seasons are a major predictor of both ET and blood vessel depth, showing strongest effect in non-exposed areas, suggesting a systemic effect, possibly due to seasonal vitamin D fluctuation. Sex, age and occupational UV exposure affect ET. This study demonstrated the feasibility of D-OCT to evaluate epidermal thickness and blood vessel depth.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.