Evidence map›Paper›PMID 34109327›Full record

ArticleStatistical atlases and computational models of the heart. STACOM (Workshop)2020

A Persistent Homology-Based Topological Loss Function for Multi-class CNN Segmentation of Cardiac MRI.

Nick Byrne, James R Clough, Giovanni Montana, Andrew P King

Abstract read
In one paragraph

Article in Statistical atlases and computational models of the heart. STACOM (Workshop), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Modality-AGnostic image Cascade (MAGIC) for multi-modality cardiac substructure segmentation.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nick ByrneMedical Physics, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
James R CloughSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Giovanni MontanaWarwick Manufacturing Group, University of Warwick, Coventry, UK.
Andrew P KingSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Funding

Department of Health DRF-2017-10-085Wellcome Trust 203148
6 · The paper itself

Abstract

With respect to spatial overlap, CNN-based segmentation of short axis cardiovascular magnetic resonance (CMR) images has achieved a level of performance consistent with inter observer variation. However, conventional training procedures frequently depend on pixel-wise loss functions, limiting optimisation with respect to extended or global features. As a result, inferred segmentations can lack spatial coherence, including spurious connected components or holes. Such results are implausible, violating the anticipated topology of image segments, which is frequently known a priori. Addressing this challenge, published work has employed persistent homology, constructing topological loss functions for the evaluation of image segments against an explicit prior. Building a richer description of segmentation topology by considering all possible labels and label pairs, we extend these losses to the task of multi-class segmentation. These topological priors allow us to resolve all topological errors in a subset of 150 examples from the ACDC short axis CMR training data set, without sacrificing overlap performance.

Indexed as

CNNImage segmentationMRITopology

Identifiers

PMID34109327
PMCPMC7610940

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.